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Fabp7 Gene Detail
Summary
  • Symbol
    Fabp7
  • Name
    fatty acid binding protein 7, brain
  • Synonyms
    B-FABP, BFABP, Blbp
  • Feature Type
    protein coding gene
  • IDs
    MGI:101916
    NCBI Gene: 12140
  • Alliance
    gene page
  • Transcription Start Sites
    10 TSS
Location &
Maps
more
  • Sequence Map
    Chr10:57661019-57664546 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 10, 29.25 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    167 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_101916
 protein coding gene Chr10:57660977-57664546 (+)
129S1/SvImJ MGP_129S1SvImJ_G0017241
 protein coding gene Chr10:57162342-57165911 (+)
A/J MGP_AJ_G0017217
 protein coding gene Chr10:55494696-55498265 (+)
AKR/J MGP_AKRJ_G0017177
 protein coding gene Chr10:56654380-56657949 (+)
BALB/cJ MGP_BALBcJ_G0017179
 protein coding gene Chr10:55605374-55608943 (+)
C3H/HeJ MGP_C3HHeJ_G0017001
 protein coding gene Chr10:56883073-56886642 (+)
C57BL/6NJ MGP_C57BL6NJ_G0017637
 protein coding gene Chr10:58943037-58946606 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0015330
 protein coding gene Chr10:52333249-52336838 (+)
CAST/EiJ MGP_CASTEiJ_G0016574
 protein coding gene Chr10:56827894-56831463 (+)
CBA/J MGP_CBAJ_G0016973
 protein coding gene Chr10:61412757-61416326 (+)
DBA/2J MGP_DBA2J_G0017078
 protein coding gene Chr10:54835930-54839499 (+)
FVB/NJ MGP_FVBNJ_G0017073
 protein coding gene Chr10:54078460-54082029 (+)
LP/J MGP_LPJ_G0017153
 protein coding gene Chr10:57264297-57267866 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0017102
 protein coding gene Chr10:63627280-63630849 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0017674
 protein coding gene Chr10:56473349-56476918 (+)
PWK/PhJ MGP_PWKPhJ_G0016355
 protein coding gene Chr10:54619816-54623391 (+)
SPRET/EiJ MGP_SPRETEiJ_G0016141
 protein coding gene Chr10:56132133-56135712 (+)
WSB/EiJ MGP_WSBEiJ_G0016639
 protein coding gene Chr10:56672830-56676399 (+)



Homology
more
  • Human Ortholog
    FABP7, fatty acid binding protein 7
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    FABP7, fatty acid binding protein 7
  • Synonyms
    B-FABP, BLBP, FABPB, MRG
  • Links
    NCBI Gene ID: 2173
    neXtProt AC: NX_O15540
    UniProt: O15540

  • Chr Location
    6q22.31; chr6:122749201-122784074 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    11 phenotypes from 2 alleles in 2 genetic backgrounds
    31 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a knock-out allele exhibit increased fear memory, increased anxiety, and decreased sensitivity to DHA-induced NMDA currents.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    15
  • GO References
    8
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    1356
  • Tissues
    242
  • cDNA Data
    42
  • Literature Summary
    316
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 12140 NCBI Gene Model | MGI Sequence Detail 3528 C57BL/6J ±  kb
    transcript NM_021272 RefSeq | MGI Sequence Detail 762 C57BL/6  
    polypeptide P51880 UniProt | EBI | MGI Sequence Detail 132 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 52
      Genomic 1
      cDNA 44
      Primer pair 4
      Other 3

      Microarray probesets 4
    Other
    Accession IDs
    less
    MGD-MRK-18745
    References
    more
    • Summaries
      All 384
      Developmental Gene Expression 316
      Gene Ontology 8
      Phenotypes 31
    • Earliest
      J:109968 Roderick TH, et al., Nineteen paracentric chromosomal inversions in mice. Genetics. 1974 Jan;76(1):109-17
    • Latest
      J:354315 Lowenstein ED, et al., Molecular Characterization of Nodose Ganglia Development Reveals a Novel Population of Phox2b+ Glial Progenitors in Mice. J Neurosci. 2024 Jul 10;44(28)
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    11/19/2024
    MGI 6.24     		The Jackson Laboratory