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Tex2 Gene Detail
Summary
  • Symbol
    Tex2
  • Name
    testis expressed gene 2
  • Synonyms
    4930568E07Rik, Def-5, mKIAA1738, Taz4
  • Feature Type
    protein coding gene
  • IDs
    MGI:102465
    NCBI Gene: 21763
  • Alliance
  • Transcription Start Sites
    18 TSS
Location &
Maps
more
  • Sequence Map
    Chr11:106392973-106504249 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 11, 69.46 cM, cytoband D
  • Mapping Data
    6 experiments
Strain
Comparison
more
  • SNPs within 2kb
    3179 from dbSNP Build 142
  • Strain Annotations
    18
  • RFLP
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_102465
protein coding gene Chr11:106392965-106504259 (-)
129S1/SvImJ MGP_129S1SvImJ_G0019309
protein coding gene Chr11:109801806-109925761 (-)
A/J MGP_AJ_G0019277
protein coding gene Chr11:105128693-105240537 (-)
AKR/J MGP_AKRJ_G0019246
protein coding gene Chr11:108259585-108377390 (-)
BALB/cJ MGP_BALBcJ_G0019251
protein coding gene Chr11:105537932-105651554 (-)
C3H/HeJ MGP_C3HHeJ_G0019060
protein coding gene Chr11:108553783-108670758 (-)
C57BL/6NJ MGP_C57BL6NJ_G0019701
protein coding gene Chr11:113175866-113302086 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0017325
protein coding gene Chr11:102405533-102515027 (-)
CAST/EiJ MGP_CASTEiJ_G0018613
protein coding gene Chr11:109628468-109744305 (-)
CBA/J MGP_CBAJ_G0019029
protein coding gene Chr11:117874932-118006546 (-)
DBA/2J MGP_DBA2J_G0019141
protein coding gene Chr11:104598372-104710697 (-)
FVB/NJ MGP_FVBNJ_G0019132
protein coding gene Chr11:104106410-104220683 (-)
LP/J MGP_LPJ_G0019211
protein coding gene Chr11:110241041-110368772 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0019162
protein coding gene Chr11:117142247-117259146 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0019738
protein coding gene Chr11:108752241-108873417 (-)
PWK/PhJ MGP_PWKPhJ_G0018378
protein coding gene Chr11:105694315-105811523 (-)
SPRET/EiJ MGP_SPRETEiJ_G0018169
protein coding gene Chr11:108532994-108658550 (-)
WSB/EiJ MGP_WSBEiJ_G0018664
protein coding gene Chr11:108732808-108852501 (-)



Homology
more
  • Human Ortholog
    TEX2, testis expressed 2
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    TEX2, testis expressed 2
  • Synonyms
    HT008, TMEM96
  • Links
    NCBI Gene ID: 55852
    neXtProt AC: NX_Q8IWB9
    UniProt: Q8IWB9

  • Chr Location
    17q23.3; chr17:64147227-64263260 (-)  GRCh38

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    18 phenotypes from 2 alleles in 2 genetic backgrounds
    14 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
  • Comparison Matrix
  • Sequences &
    Gene Models
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    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000040548 Ensembl Gene Model | MGI Sequence Detail 111277 C57BL/6J ±  kb
    transcript ENSMUST00000042780 Ensembl | MGI Sequence Detail 4934 Not Applicable  
    polypeptide ENSMUSP00000041985 Ensembl | MGI Sequence Detail 1128 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    • UniProt
      7 Sequences
    • Protein Ontology
      PR:000016256 testis-expressed protein 2
    • InterPro Domains
      IPR031468 Synaptotagmin-like mitochondrial-lipid-binding domain
    • GlyGen
      Q6ZPJ0 4 sites, 2 N-linked glycans (2 sites), 1 O-linked glycan (2 sites)
    Molecular
    Reagents
    less
    • All nucleic 13
      Genomic 1
      cDNA 12

      Microarray probesets 6
    Other
    Accession IDs
    less
    MGD-MRK-19302, MGI:1915001, MGI:2144222
    References
    more
    • Summaries
      All 45
      Developmental Gene Expression 2
      Gene Ontology 4
      Phenotypes 14
    • Earliest
      J:18471 Lemaire L, et al., Chromosomal assignment of three novel mouse genes expressed in testicular cells. Genomics. 1994 May 15;21(2):409-14
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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    last database update
    11/12/2024
    MGI 6.24
    The Jackson Laboratory