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mt-Cytb Gene Detail
Summary
  • Symbol
    mt-Cytb
  • Name
    mitochondrially encoded cytochrome b
  • Synonyms
    Cytb
  • Feature Type
    protein coding gene
  • IDs
    MGI:102501
    NCBI Gene: 17711
  • Alliance
    gene page
  • Transcription Start Sites
    20 TSS
Location &
Maps
more
  • Sequence Map
    ChrMT:14145-15288 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome MT, Syntenic
Strain
Comparison
more
  • SNPs within 2kb
    8 from dbSNP Build 142
  • Strain Annotations
    15
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_102501
 protein coding gene ChrMT:14145-15288 (+)
129S1/SvImJ MGP_129S1SvImJ_G0028394
 protein coding gene Chr4:79519709-79520852 (+)
A/J MGP_AJ_G0028355
 protein coding gene Chr4:76773700-76775569 (+)
AKR/J MGP_AKRJ_G0028303
 protein coding gene Chr4:78705573-78709625 (+)
BALB/cJ MGP_BALBcJ_G0028375
 protein coding gene Chr4:76987274-76988417 (+)
C3H/HeJ MGP_C3HHeJ_G0028090
 protein coding gene Chr4:79331140-79333838 (+)
C57BL/6NJ MGP_C57BL6NJ_G0028814
 protein coding gene Chr4:82626600-82627743 (+)
CAROLI/EiJ no annotation
CAST/EiJ MGP_CASTEiJ_G0027531
 protein coding gene Chr4:77313801-77314944 (+)
CBA/J MGP_CBAJ_G0028059
 protein coding gene Chr4:85222783-85223926 (+)
DBA/2J MGP_DBA2J_G0028208
 protein coding gene Chr4:76520040-76521183 (+)
FVB/NJ MGP_FVBNJ_G0028174
 protein coding gene Chr4:75547748-75548891 (+)
LP/J MGP_LPJ_G0028308
 protein coding gene Chr4:79863417-79864560 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0028203
 protein coding gene Chr4:90147201-90148344 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0028851
 protein coding gene Chr4:78836313-78837456 (+)
PWK/PhJ no annotation
SPRET/EiJ no annotation
WSB/EiJ MGP_WSBEiJ_G0027607
 protein coding gene Chr4:78951974-78953117 (+)



Homology
more
  • Human Ortholog
    CYTB, cytochrome b
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    CYTB, cytochrome b
  • Synonyms
    MTCYB
  • Links
    NCBI Gene ID: 4519
    neXtProt AC: NX_P00156
    UniProt: P00156

  • Chr Location
    chrMT:14747-15887 (+)  GRCh38
Human Diseases
more
  • Diseases
    2 with human CYTB associations

Human Disease Mouse Models
      
IDs
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    38
  • GO References
    13
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    16
  • Literature Summary
    10
Sequences &
Gene Models
less
  • All Sequences
    78
  • RefSeq
    1
  • UniProt
    5
Representative SequencesLengthStrain/SpeciesFlank
genomic 17711 NCBI Gene Model | MGI Sequence Detail 1144 C57BL/6J ±  kb
transcript BC004586 GenBank | ENA | DDBJ | MGI Sequence Detail 1152 CZECHII  
polypeptide P00158 UniProt | EBI | MGI Sequence Detail 381 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 69
    cDNA 17
    Other 52

    Microarray probesets 1
Other
Accession IDs
less
MGD-MRK-19338, MGI:2140441, MGI:2140442, MGI:2140448, MGI:2141054
References
more
  • Summaries
    All 51
    Developmental Gene Expression 10
    Gene Ontology 13
    Phenotypes 5
  • Earliest
    J:22484 Bibb MJ, et al., Sequence and gene organization of mouse mitochondrial DNA. Cell. 1981 Oct;26(2 Pt 2):167-80
  • Latest
    J:355679 Vercellino I, et al., SCAF1 drives the compositional diversity of mammalian respirasomes. Nat Struct Mol Biol. 2024 Jul;31(7):1061-1071
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/17/2024
MGI 6.24 		The Jackson Laboratory