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Defa-rs4 Gene Detail
Summary
  • Symbol
    Defa-rs4
  • Name
    defensin, alpha,, related sequence 4
  • Synonyms
    CRS4C-1a, CRS4C1a, Defcr-rs4
  • Feature Type
    protein coding gene
  • IDs
    MGI:102512
    NCBI Gene: 13223
  • Alliance
    gene page
Location &
Maps
more
  • Sequence Map
    Genome coordinates not available from the current reference assembly.
  • Genetic Map
    Chromosome 8, Syntenic
  • Mapping Data
    1 experiment
Homology
less
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
    6
  • GO References
    1
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
    1
  • Other Mouse Links
    GEO
Sequences &
Gene Models
less
  • All Sequences
    6
  • RefSeq
    2
  • UniProt
    1
Representative SequencesLengthStrain/SpeciesFlank
genomic AF178044 GenBank | ENA | DDBJ | MGI Sequence Detail 559 129X1/SvJ ±  kb
transcript NM_001005418 RefSeq | MGI Sequence Detail 336 C3H/HeN  
polypeptide NP_001005418 RefSeq | MGI Sequence Detail 91 C3H/HeN  
For the selected sequence
Protein
Information
less
  • UniProt
    1 Sequence
  • InterPro Domains
    IPR016327 Alpha-defensin
    IPR002366 Alpha-defensin, N-terminal
Molecular
Reagents
less
  • All nucleic 1
    cDNA 1
Other
Accession IDs
less
MGD-MRK-19350
References
more
  • Summaries
    All 7
    Gene Ontology 1
  • Earliest
    J:21466 Huttner KM, et al., A family of defensin-like genes codes for diverse cysteine-rich peptides in mouse Paneth cells. Genomics. 1994 Nov 1;24(1):99-109
  • Latest
    J:91749 Hornef MW, et al., Increased diversity of intestinal antimicrobial peptides by covalent dimer formation. Nat Immunol. 2004 Aug;5(8):836-43
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory