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Rph3a Gene Detail
Summary
  • Symbol
    Rph3a
  • Name
    rabphilin 3A
  • Synonyms
    2900002P20Rik, Doc2 family
  • Feature Type
    protein coding gene
  • IDs
    MGI:102788
    NCBI Gene: 19894
  • Alliance
    gene page
  • Transcription Start Sites
    13 TSS
Location &
Maps
more
  • Sequence Map
    Chr5:121078562-121148155 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 5, 61.17 cM
  • Mapping Data
    4 experiments
Strain
Comparison
more
  • SNPs within 2kb
    2122 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_102788
 protein coding gene Chr5:121078562-121184249 (-)
129S1/SvImJ MGP_129S1SvImJ_G0030021
 protein coding gene Chr5:124374669-124448772 (-)
A/J MGP_AJ_G0029986
 protein coding gene Chr5:119272307-119342818 (-)
AKR/J MGP_AKRJ_G0029924
 protein coding gene Chr5:123117828-123194167 (-)
BALB/cJ MGP_BALBcJ_G0029997
 protein coding gene Chr5:120652910-120723385 (-)
C3H/HeJ MGP_C3HHeJ_G0029715
 protein coding gene Chr5:123687040-123757862 (-)
C57BL/6NJ MGP_C57BL6NJ_G0030450
 protein coding gene Chr5:129107590-129186488 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0027676
 protein coding gene Chr5:113952008-114022703 (-)
CAST/EiJ MGP_CASTEiJ_G0029123
 protein coding gene Chr5:122775533-122852667 (-)
CBA/J MGP_CBAJ_G0029684
 protein coding gene Chr5:134153578-134236027 (-)
DBA/2J MGP_DBA2J_G0029834
 protein coding gene Chr5:119342705-119413268 (-)
FVB/NJ MGP_FVBNJ_G0029791
 protein coding gene Chr5:118273778-118346359 (-)
LP/J MGP_LPJ_G0029923
 protein coding gene Chr5:124895470-124972796 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0029821
 protein coding gene Chr5:138078538-138151766 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0030491
 protein coding gene Chr5:122625689-122695793 (-)
PWK/PhJ MGP_PWKPhJ_G0028837
 protein coding gene Chr5:118087945-118164617 (-)
SPRET/EiJ MGP_SPRETEiJ_G0028674
 protein coding gene Chr5:120404618-120474862 (-)
WSB/EiJ MGP_WSBEiJ_G0029198
 protein coding gene Chr5:123276176-123352674 (-)



Homology
more
  • Human Ortholog
    RPH3A, rabphilin 3A
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    RPH3A, rabphilin 3A
  • Links
    NCBI Gene ID: 22895
    neXtProt AC: NX_Q9Y2J0
    UniProt: Q9Y2J0

  • Chr Location
    12q24.13; chr12:112570380-112898881 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    5 phenotypes from multigenic genotypes
    19 phenotype references
Homozygous mutants are viable and fertile and do not exhibit any obvious abnormal phenotypes.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    52
  • GO References
    10
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    710
  • Tissues
    3
  • cDNA Data
    47
  • Literature Summary
    9
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000029608 Ensembl Gene Model | MGI Sequence Detail 69594 C57BL/6J ±  kb
transcript ENSMUST00000079204 Ensembl | MGI Sequence Detail 4150 Not Applicable  
polypeptide ENSMUSP00000078198 Ensembl | MGI Sequence Detail 681 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 49
    Genomic 1
    cDNA 47
    Other 1

    Microarray probesets 4
Other
Accession IDs
less
MGD-MRK-19696, MGI:1917466, MGI:2141069, MGI:2141154
References
more
  • Summaries
    All 69
    Developmental Gene Expression 9
    Gene Ontology 10
    Phenotypes 19
  • Earliest
    J:134667 Roderick TH, et al., Two radiation-induced chromosomal inversions in mice (Mus musculus). Proc Natl Acad Sci U S A. 1970 Oct;67(2):961-7
  • Latest
    J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory