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Cbr2 Gene Detail
Summary
  • Symbol
    Cbr2
  • Name
    carbonyl reductase 2
  • Synonyms
    lung carbonyl reductase, MLCR
  • Feature Type
    protein coding gene
  • IDs
    MGI:107200
    NCBI Gene: 12409
  • Alliance
    gene page
  • Transcription Start Sites
    23 TSS
Location &
Maps
more
  • Sequence Map
    Chr11:120620311-120622851 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 11, 84.47 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    151 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_107200
 protein coding gene Chr11:120620311-120622940 (-)
129S1/SvImJ MGP_129S1SvImJ_G0019526
 protein coding gene Chr11:125216244-125220464 (-)
A/J MGP_AJ_G0019494
 protein coding gene Chr11:119639566-119642752 (-)
AKR/J MGP_AKRJ_G0019464
 protein coding gene Chr11:123258457-123261290 (-)
BALB/cJ MGP_BALBcJ_G0019469
 protein coding gene Chr11:119999805-120003449 (-)
C3H/HeJ MGP_C3HHeJ_G0019275
 protein coding gene Chr11:123588187-123591443 (-)
C57BL/6NJ MGP_C57BL6NJ_G0019917
 protein coding gene Chr11:129000247-129004786 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0017543
 protein coding gene Chr11:116630603-116633159 (-)
CAST/EiJ MGP_CASTEiJ_G0018829
 protein coding gene Chr11:125086319-125090801 (-)
CBA/J MGP_CBAJ_G0019246
 protein coding gene Chr11:134036152-134039009 (-)
DBA/2J MGP_DBA2J_G0019358
 protein coding gene Chr11:119008808-119011433 (-)
FVB/NJ MGP_FVBNJ_G0019350
 protein coding gene Chr11:118722688-118725620 (-)
LP/J MGP_LPJ_G0019430
 protein coding gene Chr11:125517631-125520464 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0019383
 protein coding gene Chr11:132876060-132879765 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0019957
 protein coding gene Chr11:123926060-123928939 (-)
PWK/PhJ MGP_PWKPhJ_G0018595
 protein coding gene Chr11:120452677-120455688 (-)
SPRET/EiJ MGP_SPRETEiJ_G0018387
 protein coding gene Chr11:123695622-123698166 (-)
WSB/EiJ MGP_WSBEiJ_G0018881
 protein coding gene Chr11:123926345-123929357 (-)



Homology
less
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotypes from 1 allele in 1 genetic background
    8 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    12
  • GO References
    6
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    832
  • Tissues
    102
  • cDNA Data
    132
  • Literature Summary
    4
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 12409 NCBI Gene Model | MGI Sequence Detail 2541 C57BL/6J ±  kb
    transcript NM_007621 RefSeq | MGI Sequence Detail 987 C57BL/6  
    polypeptide P08074 UniProt | EBI | MGI Sequence Detail 244 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 134
      cDNA 132
      Primer pair 2

      Microarray probesets 3
    Other
    Accession IDs
    less
    MGD-MRK-35661
    References
    more
    • Summaries
      All 36
      Developmental Gene Expression 4
      Gene Ontology 6
      Phenotypes 8
    • Earliest
      J:33619 Navre M, et al., A growth factor-repressible gene associated with protein kinase C-mediated inhibition of adipocyte differentiation. J Cell Biol. 1988 Jul;107(1):279-86
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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    Funding Information
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    Send questions and comments to User Support.     		last database update
    12/17/2024
    MGI 6.24     		The Jackson Laboratory