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Snap23 Gene Detail
Summary
  • Symbol
    Snap23
  • Name
    synaptosomal-associated protein 23
  • Synonyms
    SNAP-23, Sndt, Syndet
  • Feature Type
    protein coding gene
  • IDs
    MGI:109356
    NCBI Gene: 20619
  • Alliance
    gene page
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr2:120398152-120431736 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 2, 60.37 cM, cytoband E5
  • Mapping Data
    7 experiments
Strain
Comparison
more
  • SNPs within 2kb
    743 from dbSNP Build 142
  • Strain Annotations
    18
  • RFLP
    1
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_109356
 protein coding gene Chr2:120398137-120436829 (+)
129S1/SvImJ MGP_129S1SvImJ_G0026369
 protein coding gene Chr2:123434416-123468817 (+)
A/J MGP_AJ_G0026330
 protein coding gene Chr2:118384538-118418877 (+)
AKR/J MGP_AKRJ_G0026309
 protein coding gene Chr2:121687075-121722973 (+)
BALB/cJ MGP_BALBcJ_G0026343
 protein coding gene Chr2:118622060-118655793 (+)
C3H/HeJ MGP_C3HHeJ_G0026089
 protein coding gene Chr2:122178016-122214127 (+)
C57BL/6NJ MGP_C57BL6NJ_G0026790
 protein coding gene Chr2:127460318-127497042 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0024170
 protein coding gene Chr2:113398341-113433426 (+)
CAST/EiJ MGP_CASTEiJ_G0025551
 protein coding gene Chr2:122477952-122516408 (+)
CBA/J MGP_CBAJ_G0026065
 protein coding gene Chr2:131922550-131959588 (+)
DBA/2J MGP_DBA2J_G0026204
 protein coding gene Chr2:117774382-117810711 (+)
FVB/NJ MGP_FVBNJ_G0026166
 protein coding gene Chr2:116609615-116643033 (+)
LP/J MGP_LPJ_G0026305
 protein coding gene Chr2:123700364-123734649 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0026185
 protein coding gene Chr2:136228575-136268110 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0026845
 protein coding gene Chr2:121817988-121853705 (+)
PWK/PhJ MGP_PWKPhJ_G0025287
 protein coding gene Chr2:117378339-117412916 (+)
SPRET/EiJ MGP_SPRETEiJ_G0025086
 protein coding gene Chr2:120999019-121057830 (+)
WSB/EiJ MGP_WSBEiJ_G0025620
 protein coding gene Chr2:122649465-122683306 (+)



Homology
more
  • Human Ortholog
    SNAP23, synaptosome associated protein 23
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    SNAP23, synaptosome associated protein 23
  • Synonyms
    HsT17016, SNAP-23, SNAP23A, SNAP23B
  • Links
    NCBI Gene ID: 8773
    neXtProt AC: NX_O00161
    UniProt: O00161

  • Chr Location
    15q15.1-q15.2; chr15:42491129-42545356 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    6 phenotypes from 3 alleles in 3 genetic backgrounds
    23 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a knock-out allele exhibit lethality prior to E3.5.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    43
  • GO References
    12
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    709
  • Tissues
    3
  • cDNA Data
    12
  • Literature Summary
    7
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000027287 Ensembl Gene Model | MGI Sequence Detail 33585 C57BL/6J ±  kb
    transcript ENSMUST00000116437 Ensembl | MGI Sequence Detail 2730 Not Applicable  
    polypeptide ENSMUSP00000112138 Ensembl | MGI Sequence Detail 221 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 16
      Genomic 1
      cDNA 14
      Primer pair 1

      Microarray probesets 5
    Other
    Accession IDs
    less
    MGD-MRK-38401, MGI:2138756
    References
    more
    • Summaries
      All 81
      Developmental Gene Expression 7
      Gene Ontology 12
      Phenotypes 23
    • Earliest
      J:109968 Roderick TH, et al., Nineteen paracentric chromosomal inversions in mice. Genetics. 1974 Jan;76(1):109-17
    • Latest
      J:349618 Huang M, et al., SNAP-25, but not SNAP-23, is essential for photoreceptor development, survival, and function in mice. Commun Biol. 2024 Jan 5;7(1):34
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    11/19/2024
    MGI 6.24     		The Jackson Laboratory