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Ints9 Gene Detail
Summary
  • Symbol
    Ints9
  • Name
    integrator complex subunit 9
  • Synonyms
    D14Ertd231e
  • Feature Type
    protein coding gene
  • IDs
    MGI:1098533
    NCBI Gene: 210925
  • Alliance
    gene page
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr14:65187494-65277284 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 14, 33.81 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    2412 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1098533
 protein coding gene Chr14:65187494-65277284 (+)
129S1/SvImJ MGP_129S1SvImJ_G0021475
 protein coding gene Chr14:59531800-59627381 (+)
A/J MGP_AJ_G0021434
 protein coding gene Chr14:58166965-58262005 (+)
AKR/J MGP_AKRJ_G0021410
 protein coding gene Chr14:60193306-60283346 (+)
BALB/cJ MGP_BALBcJ_G0021440
 protein coding gene Chr14:58113402-58206598 (+)
C3H/HeJ MGP_C3HHeJ_G0021217
 protein coding gene Chr14:59839698-59931041 (+)
C57BL/6NJ MGP_C57BL6NJ_G0021879
 protein coding gene Chr14:62311464-62403469 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0019419
 protein coding gene Chr14:56103013-56195385 (+)
CAST/EiJ MGP_CASTEiJ_G0020734
 protein coding gene Chr14:56320330-56416071 (+)
CBA/J MGP_CBAJ_G0021184
 protein coding gene Chr14:64176922-64278858 (+)
DBA/2J MGP_DBA2J_G0021307
 protein coding gene Chr14:57826292-57914539 (+)
FVB/NJ MGP_FVBNJ_G0021286
 protein coding gene Chr14:57222066-57316377 (+)
LP/J MGP_LPJ_G0021382
 protein coding gene Chr14:60571493-60664358 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0021315
 protein coding gene Chr14:63327093-63419612 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0021902
 protein coding gene Chr14:59366856-59462772 (+)
PWK/PhJ MGP_PWKPhJ_G0020478
 protein coding gene Chr14:54531981-54619392 (+)
SPRET/EiJ MGP_SPRETEiJ_G0020311
 protein coding gene Chr14:55335982-55423535 (+)
WSB/EiJ MGP_WSBEiJ_G0020787
 protein coding gene Chr14:59685718-59776153 (+)



Homology
more
  • Human Ortholog
    INTS9, integrator complex subunit 9
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    INTS9, integrator complex subunit 9
  • Synonyms
    CPSF2L, INT9, RC74
  • Links
    NCBI Gene ID: 55756
    neXtProt AC: NX_Q9NV88
    UniProt: Q9NV88

  • Chr Location
    8p21.1; chr8:28767661-28890242 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotypes from 1 allele in 1 genetic background
    13 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    11
  • GO References
    4
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    71
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 210925 NCBI Gene Model | MGI Sequence Detail 89791 C57BL/6J ±  kb
transcript NM_001253731 RefSeq | MGI Sequence Detail 2727 ZRU/MplStud  
polypeptide Q8K114 UniProt | EBI | MGI Sequence Detail 658 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 72
    cDNA 71
    Primer pair 1

    Microarray probesets 3
Other
Accession IDs
less
MGI:2387175
References
more
  • Summaries
    All 40
    Gene Ontology 4
    Phenotypes 13
  • Earliest
    J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
  • Latest
    J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory