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Npy6r Gene Detail
Summary
  • Symbol
    Npy6r
  • Name
    neuropeptide Y receptor Y6
  • Feature Type
    protein coding gene
  • IDs
    MGI:1098590
    NCBI Gene: 18169
  • Alliance
    gene page
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr18:44403194-44410767 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 18, 23.74 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    308 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1098590
 protein coding gene Chr18:44403175-44410767 (+)
129S1/SvImJ MGP_129S1SvImJ_G0024398
 protein coding gene Chr18:43008161-43015987 (+)
A/J MGP_AJ_G0024365
 protein coding gene Chr18:41473897-41481462 (+)
AKR/J MGP_AKRJ_G0024334
 protein coding gene Chr18:42640480-42648055 (+)
BALB/cJ MGP_BALBcJ_G0024365
 protein coding gene Chr18:41568380-41575981 (+)
C3H/HeJ MGP_C3HHeJ_G0024132
 protein coding gene Chr18:42668057-42675598 (+)
C57BL/6NJ MGP_C57BL6NJ_G0024809
 protein coding gene Chr18:44505442-44513015 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0022244
 protein coding gene Chr18:41267953-41275475 (+)
CAST/EiJ MGP_CASTEiJ_G0023606
 protein coding gene Chr18:42659891-42667710 (+)
CBA/J MGP_CBAJ_G0024101
 protein coding gene Chr18:45711118-45721946 (+)
DBA/2J MGP_DBA2J_G0024231
 protein coding gene Chr18:41087232-41094767 (+)
FVB/NJ MGP_FVBNJ_G0024197
 protein coding gene Chr18:40685245-40692830 (+)
LP/J MGP_LPJ_G0024315
 protein coding gene Chr18:43031241-43038790 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0024228
 protein coding gene Chr18:47086298-47095198 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0024856
 protein coding gene Chr18:42509030-42516603 (+)
PWK/PhJ MGP_PWKPhJ_G0023350
 protein coding gene Chr18:41282215-41289957 (+)
SPRET/EiJ MGP_SPRETEiJ_G0023155
 protein coding gene Chr18:42740869-42754501 (+)
WSB/EiJ MGP_WSBEiJ_G0023669
 protein coding gene Chr18:42433542-42442993 (+)



Homology
more
  • Human Ortholog
    NPY6R, neuropeptide Y receptor Y6 (pseudogene)
  • Vertebrate Orthologs
    1
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    NPY6R, neuropeptide Y receptor Y6 (pseudogene)
  • Synonyms
    NPY1RL, NPY6RP, PP2, Y2B
  • Links
    NCBI Gene ID: 4888
    UniProt: Q99463

  • Chr Location
    5q31.2; chr5:137801193-137810755 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    41 phenotypes from 2 alleles in 2 genetic backgrounds
    6 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a reporter allele exhibit enhanced performance on the rotarod test.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    9
  • GO References
    4
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    744
  • Tissues
    25
  • cDNA Data
    8
  • Literature Summary
    3
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000038071 Ensembl Gene Model | MGI Sequence Detail 7574 C57BL/6J ±  kb
    transcript ENSMUST00000042747 Ensembl | MGI Sequence Detail 2567 Not Applicable  
    polypeptide ENSMUSP00000040797 Ensembl | MGI Sequence Detail 371 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 17
      Genomic 3
      cDNA 8
      Primer pair 1
      Other 5

      Microarray probesets 4
    References
    more
    • Summaries
      All 32
      Developmental Gene Expression 3
      Gene Ontology 4
      Phenotypes 6
    • Earliest
      J:34096 Weinberg DH, et al., Cloning and expression of a novel neuropeptide Y receptor. J Biol Chem. 1996 Jul 12;271(28):16435-8
    • Latest
      J:326541 Cyagen Biosciences Inc., Cyagen Biosciences Website. 2022;
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    11/12/2024
    MGI 6.24     		The Jackson Laboratory