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Emp2 Gene Detail
Summary
  • Symbol
    Emp2
  • Name
    epithelial membrane protein 2
  • Synonyms
    Xmp
  • Feature Type
    protein coding gene
  • IDs
    MGI:1098726
    NCBI Gene: 13731
  • Alliance
    gene page
  • Transcription Start Sites
    10 TSS
Location &
Maps
more
  • Sequence Map
    Chr16:10099613-10131832 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 16, 5.54 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    740 from dbSNP Build 142
  • Strain Annotations
    18
  • RFLP
    2
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1098726
 protein coding gene Chr16:10099613-10131832 (-)
129S1/SvImJ MGP_129S1SvImJ_G0022504
 protein coding gene Chr16:7066011-7101451 (-)
A/J MGP_AJ_G0022466
 protein coding gene Chr16:6685932-6718001 (-)
AKR/J MGP_AKRJ_G0022442
 protein coding gene Chr16:7005350-7037548 (-)
BALB/cJ MGP_BALBcJ_G0022470
 protein coding gene Chr16:6818859-6851016 (-)
C3H/HeJ MGP_C3HHeJ_G0022237
 protein coding gene Chr16:7072077-7109296 (-)
C57BL/6NJ MGP_C57BL6NJ_G0022919
 protein coding gene Chr16:7217973-7253123 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0020440
 protein coding gene Chr16:6823129-6857072 (-)
CAST/EiJ MGP_CASTEiJ_G0021764
 protein coding gene Chr16:7079143-7114273 (-)
CBA/J MGP_CBAJ_G0022206
 protein coding gene Chr16:7517830-7549996 (-)
DBA/2J MGP_DBA2J_G0022337
 protein coding gene Chr16:6689998-6722775 (-)
FVB/NJ MGP_FVBNJ_G0022313
 protein coding gene Chr16:6686129-6713724 (-)
LP/J MGP_LPJ_G0022405
 protein coding gene Chr16:7028820-7064089 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0022335
 protein coding gene Chr16:7257626-7306656 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0022932
 protein coding gene Chr16:6939159-6971361 (-)
PWK/PhJ MGP_PWKPhJ_G0021504
 protein coding gene Chr16:6891975-6925116 (-)
SPRET/EiJ MGP_SPRETEiJ_G0021334
 protein coding gene Chr16:7003522-7038793 (-)
WSB/EiJ MGP_WSBEiJ_G0021812
 protein coding gene Chr16:7011561-7044837 (-)



Homology
more
  • Human Ortholog
    EMP2, epithelial membrane protein 2
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    EMP2, epithelial membrane protein 2
  • Synonyms
    XMP
  • Links
    NCBI Gene ID: 2013
    neXtProt AC: NX_P54851
    UniProt: P54851

  • Chr Location
    16p13.13; chr16:10528422-10580632 (-)  GRCh38
Human Diseases
more
  • Diseases
    1 with Emp2 mouse models; 1 with human EMP2 associations

Human Disease Mouse Models
      
IDs
 View 1 model
      
IDs
Click on a disease name to see all genes associated with that disease.

  • Mutations/Alleles
    1 with disease annotations
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    7 phenotypes from 1 allele in 1 genetic background
    10 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    78
  • GO References
    15
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    857
  • Tissues
    38
  • cDNA Data
    84
  • Literature Summary
    8
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 13731 NCBI Gene Model | MGI Sequence Detail 32220 C57BL/6J ±  kb
    transcript NM_007929 RefSeq | MGI Sequence Detail 3440 ZRU/MplStud  
    polypeptide O88662 UniProt | EBI | MGI Sequence Detail 172 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 86
      Genomic 1
      cDNA 84
      Other 1

      Microarray probesets 7
    References
    more
    • Summaries
      All 45
      Developmental Gene Expression 8
      Diseases 1
      Gene Ontology 15
      Phenotypes 10
    • Earliest
      J:37229 Ben-Porath I, et al., Characterization of a tumor-associated gene, a member of a novel family of genes encoding membrane glycoproteins. Gene. 1996 Dec 12;183(1-2):69-75
    • Latest
      J:326541 Cyagen Biosciences Inc., Cyagen Biosciences Website. 2022;
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    11/19/2024
    MGI 6.24     		The Jackson Laboratory