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Ccpg1 Gene Detail
Summary
  • Symbol
    Ccpg1
  • Name
    cell cycle progression 1
  • Synonyms
    1700030B06Rik, 1810073J13Rik, 9430028F23Rik, D9Ertd392e
  • Feature Type
    protein coding gene
  • IDs
    MGI:1196419
    NCBI Gene: 72278
  • Alliance
    gene page
  • Transcription Start Sites
    8 TSS
Location &
Maps
more
  • Sequence Map
    Chr9:72892711-72923622 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 9, 40.08 cM, cytoband D
  • Mapping Data
    4 experiments
Strain
Comparison
more
  • SNPs within 2kb
    741 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1196419
 protein coding gene Chr9:72892692-72923622 (+)
129S1/SvImJ MGP_129S1SvImJ_G0035023
 protein coding gene Chr9:73189066-73222803 (+)
A/J MGP_AJ_G0035004
 protein coding gene Chr9:70629653-70661134 (+)
AKR/J MGP_AKRJ_G0034933
 protein coding gene Chr9:72323077-72354278 (+)
BALB/cJ MGP_BALBcJ_G0034996
 protein coding gene Chr9:70337474-70368504 (+)
C3H/HeJ MGP_C3HHeJ_G0034705
 protein coding gene Chr9:72813596-72847768 (+)
C57BL/6NJ MGP_C57BL6NJ_G0035515
 protein coding gene Chr9:75112338-75144409 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0032426
 protein coding gene Chr9:70101567-70131861 (+)
CAST/EiJ MGP_CASTEiJ_G0034027
 protein coding gene Chr9:73154047-73187460 (+)
CBA/J MGP_CBAJ_G0034678
 protein coding gene Chr9:77728906-77759685 (+)
DBA/2J MGP_DBA2J_G0034837
 protein coding gene Chr9:70346872-70377933 (+)
FVB/NJ MGP_FVBNJ_G0034779
 protein coding gene Chr9:69656290-69687233 (+)
LP/J MGP_LPJ_G0034918
 protein coding gene Chr9:73411260-73441911 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0034820
 protein coding gene Chr9:78809959-78842480 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0035537
 protein coding gene Chr9:72476190-72509265 (+)
PWK/PhJ MGP_PWKPhJ_G0033731
 protein coding gene Chr9:70623408-70654973 (+)
SPRET/EiJ MGP_SPRETEiJ_G0033564
 protein coding gene Chr9:72763349-72794047 (+)
WSB/EiJ MGP_WSBEiJ_G0034139
 protein coding gene Chr9:72412423-72443096 (+)



Homology
more
  • Human Ortholog
    CCPG1, cell cycle progression 1
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    CCPG1, cell cycle progression 1
  • Synonyms
    CPR8
  • Links
    NCBI Gene ID: 9236
    neXtProt AC: NX_Q9ULG6
    UniProt: Q9ULG6

  • Chr Location
    15q21.3; chr15:55340032-55408510 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    12 phenotypes from 2 alleles in 2 genetic backgrounds
    10 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a hypomorphic allele exhibit defective proteostasis within the lumen of the endoplasmic reticulum (ER) in pancreatic acinar cells, resulting in unrestricted ER stress and tissue injury of the exocrine pancreas.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    15
  • GO References
    4
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    796
  • Tissues
    15
  • cDNA Data
    19
  • Literature Summary
    2
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000034563 Ensembl Gene Model | MGI Sequence Detail 30912 C57BL/6J ±  kb
    transcript ENSMUST00000085350 Ensembl | MGI Sequence Detail 2969 Not Applicable  
    polypeptide ENSMUSP00000082458 Ensembl | MGI Sequence Detail 803 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    • UniProt
      5 Sequences
    • Protein Ontology
      PR:000005144 cell cycle progression protein 1
      (term hierarchy)
    • InterPro Domains
      IPR051990 Cell Cycle Progression and Pre-B-cell Leukemia Transcription Factor-Interacting
    • GlyGen
      Q640L3 2 sites, 1 N-linked glycan (1 site), 1 O-linked glycan (1 site)
    Molecular
    Reagents
    less
    • All nucleic 21
      cDNA 19
      Primer pair 2

      Microarray probesets 8
    Other
    Accession IDs
    less
    MGI:1916755, MGI:1919528, MGI:2143038, MGI:2143164, MGI:3028626
    References
    more
    • Summaries
      All 37
      Developmental Gene Expression 2
      Gene Ontology 4
      Phenotypes 10
    • Earliest
      J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    12/10/2024
    MGI 6.24     		The Jackson Laboratory