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Cyp2j6 Gene Detail
Summary
  • Symbol
    Cyp2j6
  • Name
    cytochrome P450, family 2, subfamily j, polypeptide 6
  • Feature Type
    protein coding gene
  • IDs
    MGI:1270148
    NCBI Gene: 13110
  • Member of
    Cyp2j cluster
  • Alliance
    gene page
  • Transcription Start Sites
    6 TSS
Location &
Maps
more
  • Sequence Map
    Chr4:96404375-96441898 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 4, 44.62 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    1145 from dbSNP Build 142
  • Strain Annotations
    17
  • PCR
    1
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1270148
 protein coding gene Chr4:96404375-96449835 (-)
129S1/SvImJ MGP_129S1SvImJ_G0028464
 protein coding gene Chr4:96615046-96652610 (-)
A/J MGP_AJ_G0028427
 protein coding gene Chr4:93211367-93248522 (-)
AKR/J MGP_AKRJ_G0028374
 protein coding gene Chr4:95497538-95530167 (-)
BALB/cJ MGP_BALBcJ_G0028445
 protein coding gene Chr4:93482617-93520886 (-)
C3H/HeJ MGP_C3HHeJ_G0028158
 protein coding gene Chr4:96295541-96332914 (-)
C57BL/6NJ MGP_C57BL6NJ_G0028884
 protein coding gene Chr4:100300618-100337792 (-)
CAROLI/EiJ no annotation
CAST/EiJ MGP_CASTEiJ_G0027598
 protein coding gene Chr4:94084341-94122733 (-)
CBA/J MGP_CBAJ_G0028127
 protein coding gene Chr4:103345320-103385867 (-)
DBA/2J MGP_DBA2J_G0028277
 protein coding gene Chr4:93018649-93055661 (-)
FVB/NJ MGP_FVBNJ_G0028244
 protein coding gene Chr4:91872845-91908036 (-)
LP/J MGP_LPJ_G0028377
 protein coding gene Chr4:96942076-96976623 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0028272
 protein coding gene Chr4:109113895-109153702 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0028922
 protein coding gene Chr4:95752516-95789166 (-)
PWK/PhJ MGP_PWKPhJ_G0027323
 protein coding gene Chr4:91126596-91163646 (-)
SPRET/EiJ MGP_SPRETEiJ_G0027144
 protein coding gene Chr4:93171750-93222162 (-)
WSB/EiJ MGP_WSBEiJ_G0027676
 protein coding gene Chr4:95870721-95905671 (-)



Homology
more
  • Human Ortholog
    CYP2J2, cytochrome P450 family 2 subfamily J member 2
  • Vertebrate Orthologs
    14
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    CYP2J2, cytochrome P450 family 2 subfamily J member 2
  • Synonyms
    CPJ2, CYPIIJ2
  • Links
    NCBI Gene ID: 1573
    neXtProt AC: NX_P51589
    UniProt: P51589

  • Chr Location
    1p32.1; chr1:59893308-59969212 (-)  GRCh38
Human Diseases
more
  • Diseases
    5 with human CYP2J2 associations

Human Disease Mouse Models
      
IDs
IDs
IDs
IDs
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    7 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    31
  • GO References
    9
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    923
  • Tissues
    138
  • cDNA Data
    26
  • Literature Summary
    5
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000052914 Ensembl Gene Model | MGI Sequence Detail 37524 C57BL/6J ±  kb
transcript ENSMUST00000030303 Ensembl | MGI Sequence Detail 3605 Not Applicable  
polypeptide ENSMUSP00000030303 Ensembl | MGI Sequence Detail 501 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 30
    cDNA 28
    Primer pair 2

    Microarray probesets 4
References
more
  • Summaries
    All 39
    Developmental Gene Expression 5
    Gene Ontology 9
    Phenotypes 7
  • Earliest
    J:47555 Ma J, et al., Mapping of the CYP2J cytochrome P450 genes to human chromosome 1 and mouse chromosome 4. Genomics. 1998 Apr 1;49(1):152-5
  • Latest
    J:321481 Sisignano M, et al., Targeting CYP2J to reduce paclitaxel-induced peripheral neuropathic pain. Proc Natl Acad Sci U S A. 2016 Nov 1;113(44):12544-12549
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory