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Gene Expression Data
Assay Details
Assay
Reference: J:1520 Yamaguchi TP, et al., Expression of the fibroblast growth factor receptor FGFR-1/flg during gastrulation and segmentation in the mouse embryo. Dev Biol. 1992 Jul;152(1):75-88
Assay type: RNA in situ
MGI Accession ID: MGI:1270915
Gene symbol: Fgfr1
Gene name: fibroblast growth factor receptor 1
Probe: Fgfr-1 cDNA2
Probe preparation: Antisense labelled with S35 RNA
Visualized with: Autoradiography
Assay notes: The authors did not specify which probe was used in this assay. It is possible MGI:2670369 was used instead.
Results
Specimen 1A/B: embryonic day 6.5 (more )
Note: Egg cylinder stage.
Structure Level Pattern Image Note
TS9: embryo ectoderm Present Uniform 1A/B
TS9: ectoplacental cone Absent 1A/B
TS9: extraembryonic visceral endoderm Absent 1A/B
TS28: decidua Strong 1A/B

Specimen 1C/D: embryonic day 7.75 (more )
Note: Early head-fold-stage.
Structure Level Pattern Image Note
TS11: embryo mesoderm Strong Regionally restricted 1C/D Expression was particularly strong in the distal mesoderm lateral to the primitive streak. Transcripts were low to undetectable in the anterior mesoderm.

Specimen 1E/F: embryonic day 11.0 (more )
Structure Level Pattern Image Note
TS18: brain Strong 1E/F
TS18: future spinal cord Strong 1E/F
TS18: trunk somite Present Regionally restricted 1E/F Expression was in the somitic sclerotome. Expression was confined to perichondrium and osteoblasts in the anterior part of the sclerotome-derived vertebral column, while the centers of ossification were negative.
TS18: tail somite Strong 1E/F Expression marked the caudal half of forming vertebrae.
TS18: dorsal root ganglion Absent 1E/F

Specimen 1G/H: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: vertebral cartilage condensation Present Regionally restricted 1G/H Expression was present throughout the length of the vertebral column and somites, marking the caudal half of the forming vertebrae. Expression is confined to perichondrium and osteoblasts; the centers of ossification are negative.
TS20: tail somite Present 1G/H Expression was present throughout the length of the vertebral column and somites. Expression was strong in the less well differentiated sclerotome tissues of tail somites.
TS20: urinary system Very strong 1G/H Authors state expression was present in the kidney.
TS20: head mesenchyme Present 1G/H Authors state expression was present in the craniofacial mesenchyme.
TS20: lateral ventricle Present Regionally restricted 1G/H Expression was restricted to the proliferative ependymal layer of the lateral and 4th ventricles.
TS20: dorsal root ganglion Absent 1G/H
TS20: frontal process mesenchyme Strong 1G/H
TS20: latero-nasal process mesenchyme Strong 1G/H
TS20: medial-nasal process mesenchyme Strong 1G/H
TS20: tongue Strong 1G/H
TS20: mandibular process Strong 1G/H
TS20: lung Moderate Spotted 1G/H Staining in the lungs was more diffuse than in the kidney.
TS20: gut Moderate Spotted 1G/H Staining in the intestine was more diffuse than in the kidney.
TS20: heart Absent 1G/H
TS20: liver Absent 1G/H
TS20: maxillary process mesenchyme Strong 1G/H
TS20: 4th ventricle Present Regionally restricted 1G/H Expression was restricted to the proliferative ependymal layer of the lateral and 4th ventricles.

Specimen 4A/B: embryonic day 8.5 (more )
Structure Level Pattern Image Note
TS13: trunk unsegmented mesenchyme Strong Regionally restricted 4A/B Transcripts were abundant in the most rostral part of the presomitic mesoderm immediately caudal to the last-formed somite. Transcripts were confined to a block of cells approximately the size of one somite.
TS13: head somite Strong Regionally restricted 4A/B Expression was strong within newly forming epithelial somites, but only in the rostral half. Restriction of expression to the rostral half somites was clearest in the two most recently formed somites and was less detectable in more rostral somites.
TS13: trunk somite Strong Regionally restricted 4A/B Expression was strong within newly forming epithelial somites, but only in the rostral half. Restriction of expression to the rostral half somites was clearest in the two most recently formed somites and was less detectable in more rostral somites.

Specimen 4C/D: embryonic day 11.0 (more )
Structure Level Pattern Image Note
TS18: tail dermomyotome Present Regionally restricted 4C/D Expression is in the dermatome.
TS18: tail sclerotome Present 4C/D


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last database update
06/12/2024
MGI 6.13
The Jackson Laboratory