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Gene Expression Data
Assay Details
Assay
Reference: J:22842 Hogan BL, et al., Growth factors in development: the role of TGF-Beta related polypeptide signalling molecules in embryogenesis. Development. 1994;Suppl:53-60
Assay type: RNA in situ
MGI Accession ID: MGI:1303125
Gene symbol: Bmp4
Gene name: bone morphogenetic protein 4
Probe: Bmp4 cDNA5
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen E7.5: embryonic day 7.5 (more )
Structure Level Pattern Image Note
TS11: allantois Weak
TS11: amnion Weak
TS11: primitive streak Weak Regionally restricted Expression is detected in the posterior primitive streak.

Specimen E8.5: embryonic day 8.5 (more )
Structure Level Pattern Image Note
TS13: cardiac muscle tissue Strong
TS13: hindgut diverticulum Strong
TS13: embryo mesenchyme Strong Regionally restricted Expression is detected in the mesoderm of the primitive streak and in the ventral mesoderm caudal to the last somite.
TS13: primitive streak Strong Regionally restricted Expression is detected in the mesoderm of the primitive streak and in the ventral mesoderm caudal to the last somite.

Specimen 4. A: embryonic day 9.0 (more )
Structure Level Pattern Image Note
TS15: embryo mesenchyme Strong Regionally restricted 4A Expression is detected in the posterior mesoderm.
TS15: umbilical artery Strong 4A
TS15: umbilical artery extraembryonic part Strong 4A
TS15: umbilical vein Strong 4A
TS15: umbilical vein extraembryonic part Strong 4A

Specimen 4. BD: embryonic day 9.5 (more )
Note: Fig. 4. D is a high power magnification of the specimen in Fig. 4. B.
Structure Level Pattern Image Note
TS15: embryo mesenchyme Present Regionally restricted 4B Expression is detected in the posterior mesoderm.
TS15: forelimb bud mesenchyme Present 4B , 4D

Specimen 4. E: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: forelimb bud apical ectodermal ridge Strong 4E

Specimen 4. F: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: nasal pit Present Regionally restricted 4F Expression is detected in the ectoderm of the nasal pits derived from the first branchial arch.

Specimen not shown: embryonic day 9.0-9.5 (more )
Structure Level Pattern Image Note
TS15: mesenchyme derived from somatopleure Present Posterior transcripts are localized in the somatopleure and splanchnopleure mesoderm.
TS15: mesenchyme derived from splanchnopleure Present Posterior transcripts are localized in the somatopleure and splanchnopleure mesoderm.
TS15: limb mesenchyme Present
TS15: diencephalon Present Regionally restricted Expression is detected in the neuroepithelium of the diencephalon.
TS15: branchial arch ectoderm Present
TS15: cardiac muscle tissue Present


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
09/17/2024
MGI 6.24
The Jackson Laboratory