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Gene Expression Data
Assay Details
Assay
Reference: J:50306 Lakkis MM, et al., Neurofibromin modulation of ras activity is required for normal endocardial-mesenchymal transformation in the developing heart. Development. 1998 Nov;125(22):4359-67
Assay type: RNA in situ
MGI Accession ID: MGI:1303279
Gene symbol: Nf1
Gene name: neurofibromin 1
Probe: pkS-NfG
Probe preparation: Antisense labelled with S35 RNA
Results
Specimen 10.5: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: embryo Present Uniform 1A
TS17: dorsal root ganglion Strong 1A
Specimen 11.5: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: endocardial cushion Present 1B Nf1 expression was seen beginning at E11.5 in endocardial cushions in the AV region and in the outflow tract.
TS19: heart Weak Regionally restricted 1B A low level of expression was detected in the myocardium.
TS19: neural tube Present 1B
TS19: limb Present 1B Nf1 expression was seen in the limb mesenchyme.
Specimen 12.5: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: limb Present 1C Nf1 expression was seen in the limb mesenchyme.
TS20: heart Weak Regionally restricted 1C A low level of expression was detected in the myocardium.
TS20: endocardial cushion Present 1C
Specimen 13.5: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: endocardial cushion Present 1D
TS21: heart Weak Regionally restricted 1D A low level of expression was detected in the myocardium.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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12/10/2024
MGI 6.24 		The Jackson Laboratory