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Gene Expression Data
Assay Details
Assay
Reference: J:46379 Wang W, et al., Inner ear and maternal reproductive defects in mice lacking the Hmx3 homeobox gene. Development. 1998 Feb;125(4):621-34
Assay type: RNA in situ
MGI Accession ID: MGI:1310071
Gene symbol: Wnt7a
Gene name: wingless-type MMTV integration site family, member 7A
Probe: Wnt7A probe1
Probe preparation: Antisense labelled with S35 RNA
Results
Specimen 7 uonpregnant +/+: postnatal adult (more )
Structure Level Pattern Image Note
TS28: uterus Present Regionally restricted 7_Wnt7A unpregnant +/+ Wnt7A is restricted to the luminal epithelium and immediately adjacent stroma, but is absent from the myometrium or glandular epithelium.
Specimen 7 unpregnant -/-: postnatal adult; Hmx3tm2Tlu/Hmx3tm2Tlu (more )
Note: It is unclear whether the null mice are carrying the neo or the lacZ allele. The assays have been annotated using the lacZ allele but the neo allele could have been used instead.
Structure Level Pattern Image Note
TS28: uterus Present Regionally restricted 7_Wnt7A unpregnant -/- Wnt7A is restricted to the luminal epithelium and immediately adjacent stroma, but is absent from the myometrium or glandular epithelium.
Specimen 7 pregnant +/+: postnatal adult (more )
Structure Level Pattern Image Note
TS28: uterus Present Regionally restricted 7_Wnt7A pregnant +/+ Wnt7A expression decreases in the luminal epithelium and specifically increases in the myometrium.
Specimen 7 pregnant -/-: postnatal adult; Hmx3tm2Tlu/Hmx3tm2Tlu (more )
Note: It is unclear whether the null mice are carrying the neo or the lacZ allele. The assays have been annotated using the lacZ allele but the neo allele could have been used instead.
Structure Level Pattern Image Note
TS28: uterus Present Regionally restricted 7_Wnt7A pregnant -/- The expression of Wnt7A fails to upregulate in the myometrial layer and shows a marked increase in the expressionin the luminal epithelium relative to wild-type uteri.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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06/12/2024
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