Lif RNA in situ Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:46379 Wang W, et al., Inner ear and maternal reproductive defects in mice lacking the Hmx3 homeobox gene. Development. 1998 Feb;125(4):621-34
Assay type:	RNA in situ
MGI Accession ID:	MGI:1312924
Gene symbol:	Lif
Gene name:	leukemia inhibitory factor

Probe:	LIF probe1
Probe preparation:	Antisense labelled with S35 RNA

Results

8_LIF unpregnant +/+ ©

Specimen wild-type nonpregnant: postnatal adult (more

)

Structure	Level	Pattern	Image	Note
TS28: uterus	Present		8_LIF unpregnant +/+

8_LIF unpregnant -/- ©

Specimen nonpregnant Hmx3 null: postnatal adult; Hmx3^tm2Tlu/Hmx3^tm2Tlu (more

)
Note: It is unclear whether the null mice are carrying the neo or the lacZ allele. The assays have been annotated using the lacZ allele but the neo allele could have been used instead.

Structure	Level	Pattern	Image	Note
TS28: uterus	Present		8_LIF unpregnant -/-

8_LIF pregnant +/+ ©

Specimen wild-type pregnant: postnatal adult (more

)

Structure	Level	Pattern	Image	Note
TS28: uterus	Present		8_LIF pregnant +/+	At the time of implantation, the glandular epithelium shows a burst of LIF expression.

Specimen pregnant Hmx3 null: postnatal adult; Hmx3^tm2Tlu/Hmx3^tm2Tlu (more

)
Note: It is unclear whether the null mice are carrying the neo or the lacZ allele. The assays have been annotated using the lacZ allele but the neo allele could have been used instead.

Structure	Level	Pattern	Image	Note
TS28: uterus	Present		8_LIF pregnant -/-	LIF fails to show any increase in expression in the glandular epithelium, or in any uterine tissue.

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 12/17/2024 MGI 6.24