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Oc90 Gene Detail
Summary
  • Symbol
    Oc90
  • Name
    otoconin 90
  • Synonyms
    Ocn-95, PLA2L, Pla2ll
  • Feature Type
    protein coding gene
  • IDs
    MGI:1313269
    NCBI Gene: 18256
  • Alliance
    gene page
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr15:65747902-65784246 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 15, 29.16 cM
  • Mapping Data
    7 experiments
Strain
Comparison
more
  • SNPs within 2kb
    1333 from dbSNP Build 142
  • Strain Annotations
    18
  • PCR
    2
  • RFLP
    1
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1313269
 protein coding gene Chr15:65747899-65784260 (-)
129S1/SvImJ MGP_129S1SvImJ_G0021901
 protein coding gene Chr15:65373149-65417682 (-)
A/J MGP_AJ_G0021860
 protein coding gene Chr15:62876770-62912370 (-)
AKR/J MGP_AKRJ_G0021842
 protein coding gene Chr15:64636522-64674530 (-)
BALB/cJ MGP_BALBcJ_G0021867
 protein coding gene Chr15:63065524-63103770 (-)
C3H/HeJ MGP_C3HHeJ_G0021640
 protein coding gene Chr15:64746692-64785572 (-)
C57BL/6NJ MGP_C57BL6NJ_G0022306
 protein coding gene Chr15:67897664-67957295 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0019843
 protein coding gene Chr15:59699962-59734308 (-)
CAST/EiJ MGP_CASTEiJ_G0021159
 protein coding gene Chr15:65403090-65436892 (-)
CBA/J MGP_CBAJ_G0021606
 protein coding gene Chr15:70196366-70230624 (-)
DBA/2J MGP_DBA2J_G0021731
 protein coding gene Chr15:62679092-62715520 (-)
FVB/NJ MGP_FVBNJ_G0021713
 protein coding gene Chr15:61718884-61754934 (-)
LP/J MGP_LPJ_G0021803
 protein coding gene Chr15:65258434-65299718 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0021736
 protein coding gene Chr15:75278934-75317202 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0022328
 protein coding gene Chr15:65009995-65046732 (-)
PWK/PhJ MGP_PWKPhJ_G0020900
 protein coding gene Chr15:62765666-62801083 (-)
SPRET/EiJ MGP_SPRETEiJ_G0020741
 protein coding gene Chr15:64863996-64899644 (-)
WSB/EiJ MGP_WSBEiJ_G0021211
 protein coding gene Chr15:64987077-65023259 (-)



Homology
more
  • Human Ortholog
    OC90, otoconin 90
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    6 phenotypes from 1 allele in 1 genetic background
    1 phenotype from multigenic genotypes
    31 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a null allele exhibit reduced, enlarged, and loose otoliths, and thin cupula, saccule, utricle and tectorial membranes.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    16
  • GO References
    8
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    828
  • Tissues
    41
  • cDNA Data
    15
  • Literature Summary
    15
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000015001 Ensembl Gene Model | MGI Sequence Detail 36345 C57BL/6J ±  kb
    transcript ENSMUST00000060522 Ensembl | MGI Sequence Detail 1909 Not Applicable  
    polypeptide ENSMUSP00000062865 Ensembl | MGI Sequence Detail 485 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 26
      Genomic 3
      cDNA 17
      Primer pair 6

      Microarray probesets 4
    Other
    Accession IDs
    less
    MGD-MRK-38290, MGI:109245
    References
    more
    • Summaries
      All 73
      Developmental Gene Expression 15
      Diseases 1
      Gene Ontology 8
      Phenotypes 31
    • Earliest
      J:109968 Roderick TH, et al., Nineteen paracentric chromosomal inversions in mice. Genetics. 1974 Jan;76(1):109-17
    • Latest
      J:332093 Szeto IYY, et al., SOX9 and SOX10 control fluid homeostasis in the inner ear for hearing through independent and cooperative mechanisms. Proc Natl Acad Sci U S A. 2022 Nov 16;119(46):e2122121119
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    11/12/2024
    MGI 6.24     		The Jackson Laboratory