About   Help   FAQ
Taf1 Gene Detail
Summary
  • Symbol
    Taf1
  • Name
    TATA-box binding protein associated factor 1
  • Synonyms
    B430306D02Rik, Ccg-1, Ccg1, KAT4, Taf2a
  • Feature Type
    protein coding gene
  • IDs
    MGI:1336878
    NCBI Gene: 270627
  • Alliance
    gene page
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    ChrX:100576335-100644635 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome X, 44.29 cM
  • Mapping Data
    16 experiments
Strain
Comparison
more
  • SNPs within 2kb
    1225 from dbSNP Build 142
  • Strain Annotations
    18
  • RFLP
    2
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1336878
 protein coding gene ChrX:100576335-100645395 (+)
129S1/SvImJ MGP_129S1SvImJ_G0035963
 protein coding gene ChrX:98053561-98128160 (+)
A/J MGP_AJ_G0035948
 protein coding gene ChrX:98046995-98117087 (+)
AKR/J MGP_AKRJ_G0035864
 protein coding gene ChrX:100873548-100944351 (+)
BALB/cJ MGP_BALBcJ_G0035931
 protein coding gene ChrX:96796819-96865609 (+)
C3H/HeJ MGP_C3HHeJ_G0035640
 protein coding gene ChrX:98457130-98527525 (+)
C57BL/6NJ MGP_C57BL6NJ_G0036460
 protein coding gene ChrX:100964804-101039221 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0033290
 protein coding gene ChrX:95784123-95853286 (+)
CAST/EiJ MGP_CASTEiJ_G0034927
 protein coding gene ChrX:82759234-82831498 (+)
CBA/J MGP_CBAJ_G0035615
 protein coding gene ChrX:104094484-104170951 (+)
DBA/2J MGP_DBA2J_G0035769
 protein coding gene ChrX:97263247-97332661 (+)
FVB/NJ MGP_FVBNJ_G0035707
 protein coding gene ChrX:96639258-96710152 (+)
LP/J MGP_LPJ_G0035859
 protein coding gene ChrX:99005447-99077024 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0035742
 protein coding gene ChrX:108630531-108708439 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0036487
 protein coding gene ChrX:97740826-97812402 (+)
PWK/PhJ MGP_PWKPhJ_G0034626
 protein coding gene ChrX:80359504-80430770 (+)
SPRET/EiJ MGP_SPRETEiJ_G0034454
 protein coding gene ChrX:83668694-83742974 (+)
WSB/EiJ MGP_WSBEiJ_G0035066
 protein coding gene ChrX:96446805-96519995 (+)



Homology
more
  • Human Ortholog
    TAF1, TATA-box binding protein associated factor 1
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    TAF1, TATA-box binding protein associated factor 1
  • Synonyms
    BA2R, CCG1, CCGS, DYT3, DYT3/TAF1, KAT4, MRXS33, NSCL2, N-TAF1, OF, P250, TAF2A, TAF(II)250, TAFII-250, TAFII250, XDP
  • Links
    NCBI Gene ID: 6872
    neXtProt AC: NX_P21675
    UniProt: P21675

  • Chr Location
    Xq13.1; chrX:71366136-71532374 (+)  GRCh38
  • Human Ortholog
    TAF1L, TATA-box binding protein associated factor 1 like
  • Synonyms
    TAF2A2, TAF(II)210
  • Links
    NCBI Gene ID: 138474
    neXtProt AC: NX_Q8IZX4
    UniProt: Q8IZX4

  • Chr Location
    9p21.1; chr9:32629454-32635669 (-)  GRCh38
Human Diseases
more
  • Diseases
    2 with human TAF1 associations

Human Disease Mouse Models
      
IDs
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    94
  • GO References
    16
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    857
  • Tissues
    92
  • cDNA Data
    123
  • Literature Summary
    14
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 270627 NCBI Gene Model | MGI Sequence Detail 68301 C57BL/6J ±  kb
transcript NM_001290729 RefSeq | MGI Sequence Detail 7168 ZRU/MplStud  
polypeptide Q80UV9 UniProt | EBI | MGI Sequence Detail 1891 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 127
    cDNA 125
    Primer pair 2

    Microarray probesets 3
Other
Accession IDs
less
MGD-MRK-1796, MGD-MRK-1797, MGI:2147953, MGI:88292
References
more
  • Summaries
    All 73
    Developmental Gene Expression 14
    Gene Ontology 16
    Phenotypes 5
  • Earliest
    J:12527 Derry JM, et al., Localization of the Ccg1 gene on the mouse X Chromosome. Cytogenet Cell Genet. 1989;51:988 (Abstr.)
  • Latest
    J:352096 Crombie EM, et al., Taf1 knockout is lethal in embryonic male mice and heterozygous females show weight and movement disorders. Dis Model Mech. 2024 Jul 1;17(7)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory