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Gene Expression Data
Assay Details
Assay
Reference: J:56092 Huh S, et al., Dorsal-ventral patterning defects in the eye of BF-1-deficient mice associated with a restricted loss of shh expression. Dev Biol. 1999 Jul 1;211(1):53-63
Assay type: RNA in situ
MGI Accession ID: MGI:1340808
Gene symbol: Pax6
Gene name: paired box 6
Probe: Pax6 probe5
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen 3A: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: pigmented retinal epithelium Present Regionally restricted 3A Expression is in the optic cup.
TS20: retina Present Regionally restricted 3A Expression is in the optic cup.

Specimen 3B: embryonic day 12.5; Foxg1tm1M/Foxg1tm1M (more )
Structure Level Pattern Image Note
TS20: eye Present Regionally restricted 3B In this mutant, expression is expanded ventrally and medially toward the ventral forebrain.

Specimen 5D: embryonic day 12.5; Foxg1tm1M/Foxg1tm1M (more )
Note: Sections are from lateral to medial respectively.
Structure Level Pattern Image Note
TS20: neural retinal epithelium Present Regionally restricted 5D In this mutant, ectopic expression in the proximal vesicle is not limited to cells that would express the Hfhbf1 gene. This implies a change in fate of cells in the ventral optic neuroepithelium.
TS20: pigmented retinal epithelium Present Regionally restricted 5D In this mutant, ectopic expression in the proximal vesicle is not limited to cells that would express the Hfhbf1 gene. This implies a change in fate of cells in the ventral optic neuroepithelium.

Specimen 5E: embryonic day 12.5; Foxg1tm1M/Foxg1tm1M (more )
Note: Sections are from lateral to medial respectively.
Structure Level Pattern Image Note
TS20: neural retinal epithelium Present Regionally restricted 5E In this mutant, ectopic expression in the proximal vesicle is not limited to cells that would express the Hfhbf1 gene. This implies a change in fate of cells in the ventral optic neuroepithelium.
TS20: pigmented retinal epithelium Present Regionally restricted 5E In this mutant, ectopic expression in the proximal vesicle is not limited to cells that would express the Hfhbf1 gene. This implies a change in fate of cells in the ventral optic neuroepithelium.

Specimen 5F: embryonic day 12.5; Foxg1tm1M/Foxg1tm1M (more )
Note: Sections are from lateral to medial respectively.
Structure Level Pattern Image Note
TS20: neural retinal epithelium Present Regionally restricted 5F In this mutant, ectopic expression in the proximal vesicle is not limited to cells that would express the Hfhbf1 gene. This implies a change in fate of cells in the ventral optic neuroepithelium.
TS20: pigmented retinal epithelium Present Regionally restricted 5F In this mutant, ectopic expression in the proximal vesicle is not limited to cells that would express the Hfhbf1 gene. This implies a change in fate of cells in the ventral optic neuroepithelium.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
06/12/2024
MGI 6.13
The Jackson Laboratory