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Dazap2 Gene Detail
Summary
  • Symbol
    Dazap2
  • Name
    DAZ associated protein 2
  • Synonyms
    Brbp, Gcap28, gt6-12, MGC:25222, mKIAA0058, Prtb
  • Feature Type
    protein coding gene
  • IDs
    MGI:1344344
    NCBI Gene: 23994
  • Alliance
    gene page
  • Transcription Start Sites
    13 TSS
Location &
Maps
more
  • Sequence Map
    Chr15:100513543-100518642 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 15, 56.36 cM
  • Mapping Data
    4 experiments
Strain
Comparison
more
  • SNPs within 2kb
    133 from dbSNP Build 142
  • Strain Annotations
    18
  • RFLP
    1
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1344344
 protein coding gene Chr15:100513230-100518642 (+)
129S1/SvImJ MGP_129S1SvImJ_G0022356
 protein coding gene Chr15:102596620-102603255 (+)
A/J MGP_AJ_G0022318
 protein coding gene Chr15:98555139-98560202 (+)
AKR/J MGP_AKRJ_G0022294
 protein coding gene Chr15:101567556-101572651 (+)
BALB/cJ MGP_BALBcJ_G0022322
 protein coding gene Chr15:98664658-98669762 (+)
C3H/HeJ MGP_C3HHeJ_G0022092
 protein coding gene Chr15:101645877-101650970 (+)
C57BL/6NJ MGP_C57BL6NJ_G0022770
 protein coding gene Chr15:106451990-106457645 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0020295
 protein coding gene Chr15:94306848-94311915 (+)
CAST/EiJ MGP_CASTEiJ_G0021617
 protein coding gene Chr15:102497451-102502547 (+)
CBA/J MGP_CBAJ_G0022061
 protein coding gene Chr15:110092272-110097862 (+)
DBA/2J MGP_DBA2J_G0022188
 protein coding gene Chr15:97906593-97911639 (+)
FVB/NJ MGP_FVBNJ_G0022167
 protein coding gene Chr15:96928178-96933281 (+)
LP/J MGP_LPJ_G0022259
 protein coding gene Chr15:102751109-102759821 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0022188
 protein coding gene Chr15:113823554-113829702 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0022784
 protein coding gene Chr15:101568720-101573816 (+)
PWK/PhJ MGP_PWKPhJ_G0021356
 protein coding gene Chr15:98038227-98044100 (+)
SPRET/EiJ MGP_SPRETEiJ_G0021188
 protein coding gene Chr15:101457593-101461682 (+)
WSB/EiJ MGP_WSBEiJ_G0021667
 protein coding gene Chr15:102192826-102197928 (+)



Homology
more
  • Human Ortholog
    DAZAP2, DAZ associated protein 2
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    DAZAP2, DAZ associated protein 2
  • Synonyms
    PRTB
  • Links
    NCBI Gene ID: 9802
    neXtProt AC: NX_Q15038
    UniProt: Q15038

  • Chr Location
    12q13.13; chr12:51238724-51271362 (+)  GRCh38
Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotypes from 2 alleles in 2 genetic backgrounds
    29 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a gene trap insertion are viable, fertile and do not exhibit motor coordination or balance defects.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    33
  • GO References
    6
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    938
  • Tissues
    29
  • cDNA Data
    450
  • Literature Summary
    3
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 23994 NCBI Gene Model | MGI Sequence Detail 5100 C57BL/6J ±  kb
    transcript NM_011873 RefSeq | MGI Sequence Detail 1860 Not Specified  
    polypeptide Q9DCP9 UniProt | EBI | MGI Sequence Detail 168 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 451
      cDNA 450
      Other 1

      Microarray probesets 3
    Other
    Accession IDs
    less
    MGD-MRK-18677, MGI:101853, MGI:2145972
    References
    more
    • Summaries
      All 63
      Developmental Gene Expression 3
      Diseases 1
      Gene Ontology 6
      Phenotypes 29
    • Earliest
      J:7688 Lane PW, et al., Association of megacolon with a new dominant spotting gene (Dom) in the mouse. J Hered. 1984 Nov-Dec;75(6):435-9
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    11/19/2024
    MGI 6.24     		The Jackson Laboratory