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Tenm3 Gene Detail
Summary
  • Symbol
    Tenm3
  • Name
    teneurin transmembrane protein 3
  • Synonyms
    2610100B16Rik, mKIAA1455, Odz3, Ten-m3
  • Feature Type
    protein coding gene
  • IDs
    MGI:1345183
    NCBI Gene: 23965
  • Alliance
    gene page
  • Transcription Start Sites
    15 TSS
Location &
Maps
more
  • Sequence Map
    Chr8:48680717-49296986 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 8, 27.02 cM, cytoband B2
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    16900 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1345183
 protein coding gene Chr8:48678700-51370255 (-)
129S1/SvImJ MGP_129S1SvImJ_G0033606
 protein coding gene Chr8:47449332-48102622 (-)
A/J MGP_AJ_G0033588
 protein coding gene Chr8:45583462-46213654 (-)
AKR/J MGP_AKRJ_G0033513
 protein coding gene Chr8:46918925-47559998 (-)
BALB/cJ MGP_BALBcJ_G0033585
 protein coding gene Chr8:45766238-46404676 (-)
C3H/HeJ MGP_C3HHeJ_G0033294
 protein coding gene Chr8:47494520-48130535 (-)
C57BL/6NJ MGP_C57BL6NJ_G0034101
 protein coding gene Chr8:49273969-49932539 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0031049
 protein coding gene Chr8:41813734-42441184 (-)
CAST/EiJ MGP_CASTEiJ_G0032620
 protein coding gene Chr8:46967849-47625845 (-)
CBA/J MGP_CBAJ_G0033273
 protein coding gene Chr8:51205316-51882835 (-)
DBA/2J MGP_DBA2J_G0033426
 protein coding gene Chr8:45392525-46012674 (-)
FVB/NJ MGP_FVBNJ_G0033367
 protein coding gene Chr8:44861378-45479400 (-)
LP/J MGP_LPJ_G0033514
 protein coding gene Chr8:47451703-48109877 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0033411
 protein coding gene Chr8:51223639-51890883 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0034119
 protein coding gene Chr8:47120455-47771278 (-)
PWK/PhJ MGP_PWKPhJ_G0032328
 protein coding gene Chr8:44940223-45569506 (-)
SPRET/EiJ MGP_SPRETEiJ_G0032164
 protein coding gene Chr8:46274921-46915409 (-)
WSB/EiJ MGP_WSBEiJ_G0032736
 protein coding gene Chr8:47374818-48024665 (-)



Homology
more
  • Human Ortholog
    TENM3, teneurin transmembrane protein 3
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    TENM3, teneurin transmembrane protein 3
  • Synonyms
    MCOPCB9, MCOPS15, ODZ3, ten-3, TEN3, Ten-m3, TNM3
  • Links
    NCBI Gene ID: 55714
    neXtProt AC: NX_Q9P273
    UniProt: Q9P273

  • Chr Location
    4q34.3-q35.1; chr4:181447613-182803024 (+)  GRCh38
Human Diseases
more
  • Diseases
    1 with human TENM3 associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    4 phenotypes from 1 allele in 1 genetic background
    22 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
  • All Mutations and Alleles
    81
  • Chemically induced (other)
    1
  • Endonuclease-mediated
    2
  • Gene trapped
    73
  • Targeted
    5
  • Genomic Mutations
    1 involving Tenm3
  • Incidental Mutations
    APF , CvDC
  • Find Mice (IMSR)
    225 strains or lines available
Mice homozygous for a null mutation display abnormal ipsilateral retinal ganglion cell projections and impaired performance in visually mediated behavioral tasks.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    26
  • GO References
    12
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    1042
  • Tissues
    237
  • cDNA Data
    10
  • Literature Summary
    27
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000031561 Ensembl Gene Model | MGI Sequence Detail 616270 C57BL/6J ±  kb
transcript ENSMUST00000033965 Ensembl | MGI Sequence Detail 8961 Not Applicable  
polypeptide ENSMUSP00000033965 Ensembl | MGI Sequence Detail 2715 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 24
    cDNA 13
    Primer pair 6
    Other 5

    Microarray probesets 4
Other
Accession IDs
less
MGI:1917577
References
more
  • Summaries
    All 78
    Developmental Gene Expression 27
    Gene Ontology 12
    Phenotypes 22
  • Earliest
    J:30814 Neophytou PI, et al., A subtractive cloning approach to the identification of mRNAs specifically expressed in pancreatic beta-cells. Diabetes. 1996 Feb;45(2):127-33
  • Latest
    J:357284 Lo Giudice Q, et al., Developmental emergence of first- and higher-order thalamic neuron molecular identities. Development. 2024 Sep 15;151(18)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory