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Slc27a2 Gene Detail
Summary
  • Symbol
    Slc27a2
  • Name
    solute carrier family 27 (fatty acid transporter), member 2
  • Synonyms
    ACSVL1, FATP2, FATP2, Vlac, Vlacs, VLCS
  • Feature Type
    protein coding gene
  • IDs
    MGI:1347099
    NCBI Gene: 26458
  • Alliance
    gene page
  • Transcription Start Sites
    15 TSS
Location &
Maps
more
  • Sequence Map
    Chr2:126394944-126430163 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 2, 61.76 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    1077 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1347099
 protein coding gene Chr2:126394327-126430163 (+)
129S1/SvImJ MGP_129S1SvImJ_G0026440
 protein coding gene Chr2:129769807-129811030 (+)
A/J MGP_AJ_G0026403
 protein coding gene Chr2:124510387-124549574 (+)
AKR/J MGP_AKRJ_G0026379
 protein coding gene Chr2:128085393-128123035 (+)
BALB/cJ MGP_BALBcJ_G0026415
 protein coding gene Chr2:124781730-124820053 (+)
C3H/HeJ MGP_C3HHeJ_G0026159
 protein coding gene Chr2:128563210-128599788 (+)
C57BL/6NJ MGP_C57BL6NJ_G0026861
 protein coding gene Chr2:133905059-133941968 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0024238
 protein coding gene Chr2:119244402-119280783 (+)
CAST/EiJ MGP_CASTEiJ_G0025620
 protein coding gene Chr2:128787340-128831132 (+)
CBA/J MGP_CBAJ_G0026139
 protein coding gene Chr2:138803808-138839645 (+)
DBA/2J MGP_DBA2J_G0026273
 protein coding gene Chr2:123921636-123959691 (+)
FVB/NJ MGP_FVBNJ_G0026237
 protein coding gene Chr2:122579548-122617364 (+)
LP/J MGP_LPJ_G0026378
 protein coding gene Chr2:130031512-130071293 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0026257
 protein coding gene Chr2:142879197-142921315 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0026916
 protein coding gene Chr2:128097173-128134134 (+)
PWK/PhJ MGP_PWKPhJ_G0025356
 protein coding gene Chr2:123468686-123505056 (+)
SPRET/EiJ MGP_SPRETEiJ_G0025158
 protein coding gene Chr2:127169511-127210103 (+)
WSB/EiJ MGP_WSBEiJ_G0025694
 protein coding gene Chr2:128987173-129026620 (+)



Homology
more
  • Human Ortholog
    SLC27A2, solute carrier family 27 member 2
  • Vertebrate Orthologs
    6
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    SLC27A2, solute carrier family 27 member 2
  • Synonyms
    ACSVL1, FACVL1, FATP2, hFACVL1, HsT17226, VLACS, VLCS
  • Links
    NCBI Gene ID: 11001
    neXtProt AC: NX_O14975
    UniProt: O14975

  • Chr Location
    15q21.2; chr15:50182196-50236385 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotypes from 1 allele in 1 genetic background
    1 phenotype from multigenic genotypes
    17 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Homozygous mutant mice are viable and show no gross morphological abnormalities.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    68
  • GO References
    17
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    1067
  • Tissues
    258
  • cDNA Data
    175
  • Literature Summary
    15
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 26458 NCBI Gene Model | MGI Sequence Detail 35220 C57BL/6J ±  kb
transcript NM_011978 RefSeq | MGI Sequence Detail 2309 C57BL/6  
polypeptide O35488 UniProt | EBI | MGI Sequence Detail 620 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 179
    cDNA 175
    Primer pair 3
    Other 1

    Microarray probesets 3
Other
Accession IDs
less
MGI:1330825
References
more
  • Summaries
    All 68
    Developmental Gene Expression 15
    Gene Ontology 17
    Phenotypes 17
  • Earliest
    J:109968 Roderick TH, et al., Nineteen paracentric chromosomal inversions in mice. Genetics. 1974 Jan;76(1):109-17
  • Latest
    J:324027 Kappen C, et al., Nutrient Transporter Gene Expression in the Early Conceptus-Implications From Two Mouse Models of Diabetic Pregnancy. Front Cell Dev Biol. 2022;10:777844
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory