Summary | Mutation origin | Mutation description | Expression | Phenotypes | Disease models | Tumor data | Find Mice (IMSR) | References

Symbol:	Lystbg
Name:	lysosomal trafficking regulator; beige
MGI ID:	MGI:1855968
Synonyms:	30B/22B, bg, CHS mice
Gene:	Lyst  Location: Chr13:13764982-13953388 bp, + strand  Genetic Position: Chr13, 5.28 cM
Alliance:	Lystbg page

Strain of Origin:

C3H/Rl

Allele Type:    Radiation induced Mutation:    Transposon insertion   Mutation details: This allele is an insertion of a partial LINE 1 repetitive element into an intron of the gene. The insertion included only the most 3' 1097 bp of the element producing a frameshift mutation resulting in a truncated protein predicted to be missing the last 1442 amino acids. (J:33734, J:41243) Inheritance:    Recessive

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:	6 assay results 1 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	7 anatomical structure(s)

List all tumor models in MMHCdb carrying Lystbg

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 6 strains available      Cell Lines: 0 lines available
Carrying any Lyst Mutation:	225 strains or lines available

Original:	J:29744 Kelly EM, Beige, bg. Mouse News Lett. 1957;16:36
All:	131 reference(s)