Summary | Mutation origin | Mutation description | Expression | Phenotypes | Disease models | Find Mice (IMSR) | Notes | References

Symbol: Gdf5bp-J Name: growth differentiation factor 5; brachypodism Jackson MGI ID: MGI:1855974 Synonyms: GdfbpJ Gene: Gdf5  Location: Chr2:155782943-155787204 bp, - strand  Genetic Position: Chr2, 77.26 cM Alliance: Gdf5bp-J page

Gdf5bp-J/Gdf5bp-J Show the 1 phenotype image(s) involving this allele.

Strain of Origin:

A/J

Allele Type:    Spontaneous Mutation:    Insertion   Mutation details: This remutation to brachypodism occurred in the A/J strain at The Jackson Laboratory. The mutation is caused by the insertion of a guanine residue into a stretch of three guanine residues in the gene sequence (position 1444-1448), producing a stop codon 41 amino acids later. (J:17582) Inheritance:    Recessive

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

11 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 2 strains available      Cell Lines: 0 lines available
Carrying any Gdf5 Mutation:	32 strains or lines available

Original:	J:17582 Storm EE, et al., Limb alterations in brachypodism mice due to mutations in a new member of the TGF beta-superfamily [see comments]. Nature. 1994 Apr 14;368(6472):639-43
All:	13 reference(s)