Pax6<Sey> Spontaneous Allele Detail MGI Mouse (MGI:1856155)

Pax6^Sey
Spontaneous Allele Detail

Summary

Symbol:	Pax6^Sey
Name:	paired box 6; small eye
MGI ID:	MGI:1856155
Synonyms:	P5, Pax6-, Pax6^SeyEd, sey
Gene:	Pax6 Location: Chr2:105499245-105527709 bp, + strand Genetic Position: Chr2, 55.31 cM
Alliance:	Pax6^Sey page

Development of the Pax6^Sey/Pax6⁺ lens

Show the 1 phenotype image(s) involving this allele.

Mutation
origin

Strain of Origin:

Line selected for low body weight

Mutation
description

Allele Type:		Spontaneous
Mutation:		Single point mutation
		Mutation details: A G-to-T transversion in coding nucleotide 622 (NM_001244198.2) changes the glycine codon at position 208 to a stop codon (Gly208; NP_001231127.1), resulting in premature termination before the homeobox domain. (J:2301*)
Inheritance:		Semidominant

Phenotypes

View phenotypes and curated references for all genotypes (concatenated display).

Expression

In Mice Carrying this Mutation:	873 assay results 3 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	36 anatomical structure(s)

Find Mice (IMSR)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 8 strains available Cell Lines: 0 lines available
Carrying any Pax6 Mutation:	94 strains or lines available

References

Original:	J:12101 Roberts RC, Small-eyes, a new dominant mutant in the mouse. Genet Res. 1967;9(1):121-122
All:	177 reference(s)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 11/19/2024 MGI 6.24