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Pax1un-ex
Spontaneous Allele Detail
Summary
Symbol: Pax1un-ex
Name: paired box 1; undulated extensive
MGI ID: MGI:1856223
Synonyms: hump-back syndrome and wavy tail, unex
Gene: Pax1  Location: Chr2:147203850-147216972 bp, + strand  Genetic Position: Chr2, 72.63 cM
Alliance: Pax1un-ex page
Mutation
origin
Strain of Origin:  Peru-Coppock stock
Mutation
description
Allele Type:    Spontaneous
Mutation:    Intragenic deletion
 
Mutation details: This allele comprises a deletion of at least 28.2 kb including exon 5 and the polyadenylation signal. Analyses of mutant mice indicated truncated transcript expressed at levels lower than those of wild-type. Endogenous protein was undetected in homozygous mutant mice, however the potential for a mutant protein not detected by the antiserum remained. (J:23331)
Inheritance:    Recessive
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 11 assay results
In Structures Affected by this Mutation: 11 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Pax1 Mutation:  28 strains or lines available
References
Original:  J:15087 Wallace ME, un, undulated. Mouse News Lett. 1979;61:29
All:  9 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/05/2024
MGI 6.24 		The Jackson Laboratory