Gli3<Xt> Spontaneous Allele Detail MGI Mouse (MGI:1856275)

Gli3^Xt
Spontaneous Allele Detail

Summary

Symbol:	Gli3^Xt
Name:	GLI-Kruppel family member GLI3; extra toes
MGI ID:	MGI:1856275
Synonyms:	Gli3^-, Xt^H
Gene:	Gli3 Location: Chr13:15638308-15904611 bp, + strand Genetic Position: Chr13, 5.43 cM, cytoband A2
Alliance:	Gli3^Xt page

Mutation
origin

Strain of Origin:

CBA/H x (C3H/HeH x 101/H)F1

Mutation
description

Allele Type:		Spontaneous
Mutation:		Deletion
		Gli3^Xt involves 1 genes/genome features (Gli3) View all
		Mutation details: Southern Blot analysis of genomic DNA from +/+, Xt/+ and Xt/Xt mice showed that at least part of the Gli3 gene (cDNA homologous with a 5' part of the human GLI3 gene) is deleted in the Gli3^Xt allele. (J:1718, J:3333, J:11318)
Inheritance:		Semidominant

Phenotypes

View phenotypes and curated references for all genotypes (concatenated display).

Expression

In Mice Carrying this Mutation:

235 assay results
1 RNA-Seq or microarray experiment(s)

Find Mice (IMSR)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available Cell Lines: 0 lines available
Carrying any Gli3 Mutation:	81 strains or lines available

References

Original:	J:12947 Lyon MF, et al., The overall rates of dominant and recessive lethal and visible mutation induced by spermatogonial X-irradiation of mice. Genet Res. 1964;5(3):448-467
All:	54 reference(s)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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