Summary | Mutation origin | Mutation description | Expression | Phenotypes | Disease models | Tumor data | Find Mice (IMSR) | References

Symbol: Gnrh1hpg Name: gonadotropin releasing hormone 1; hypogonadal MGI ID: MGI:1856393 Synonyms: Gnrh-, gnrhhpg, hpg Gene: Gnrh1  Location: Chr14:67982717-67986889 bp, + strand  Genetic Position: Chr14, 34.66 cM Alliance: Gnrh1hpg page

Characterization of Gnrh1hpg/Gnrh1hpg mice Show the 1 phenotype image(s) involving this allele.

Strain of Origin:

C3H101H-Rb(1.3)1Bnr

Allele Type:    Spontaneous Mutation:    Intragenic deletion   Mutation details: The mutation in the hypogonadal mouse is an approximately 33.5 kb deletion that removes two exons that encode most of the protein. (J:8515, J:14505, J:94662) Inheritance:    Recessive

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:	46 assay results 1 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	14 anatomical structure(s)

List all tumor models in MMHCdb carrying Gnrh1hpg

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 2 strains available      Cell Lines: 0 lines available
Carrying any Gnrh1 Mutation:	11 strains or lines available

Original:	J:5877 Cattanach BM, et al., Gonadotrophin-releasing hormone deficiency in a mutant mouse with hypogonadism. Nature. 1977 Sep 22;269(5626):338-40
All:	97 reference(s)