Summary | Mutation origin | Mutation description | Expression | Phenotypes | Disease models | Tumor data | Find Mice (IMSR) | Notes | References

Symbol: Egfrwa2 Name: epidermal growth factor receptor; waved 2 MGI ID: MGI:1856397 Synonyms: wa-2, wa2, waved2 Gene: Egfr  Location: Chr11:16702203-16868158 bp, + strand  Genetic Position: Chr11, 9.41 cM, cytoband A1-A4 Alliance: Egfrwa2 page

Mammary gland histology of an Egfrwa2/Egfrwa2 mouse Show the 3 phenotype image(s) involving this allele.

Strain of Origin:

STOCK ac

Allele Type:    Spontaneous Mutation:    Single point mutation   Mutation details: A T-to-G transversion mutation in the sequences encoding the tyrosine kinase domain results in a substitution of a highly conserved valine with glycine at position 767 (P.V767G) in the third kinase subdomain. (J:16986) Inheritance:    Recessive

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:	8 assay results
In Structures Affected by this Mutation:	19 anatomical structure(s)

List all tumor models in MMHCdb carrying Egfrwa2

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 3 strains available      Cell Lines: 0 lines available
Carrying any Egfr Mutation:	87 strains or lines available

Original:	J:13052 Keeler CE, A second rexoid coat character in the house mouse. J Hered. 1935;26(5):189-191
All:	70 reference(s)