Kcnj6<wv> Spontaneous Allele Detail MGI Mouse (MGI:1856525)

Kcnj6^wv
Spontaneous Allele Detail

Summary

Symbol:	Kcnj6^wv
Name:	potassium inwardly-rectifying channel, subfamily J, member 6; weaver
MGI ID:	MGI:1856525
Synonyms:	wv
Gene:	Kcnj6 Location: Chr16:94549495-94798560 bp, - strand Genetic Position: Chr16, 55.44 cM
Alliance:	Kcnj6^wv page

Kcnj6^wv/Kcnj6^wv

Show the 1 phenotype image(s) involving this allele.

Mutation
origin

Strain of Origin:

C57BL/6J

Mutation
description

Allele Type:		Spontaneous
Mutation:		Single point mutation
		Mutation details: A G-to-A transition at coding nucleotide 466 replaces a glycine with serine at amino acid residue 156 (p.G156S), affecting the highly conserved H5 domain of the channel. (J:29230, J:30864)
Inheritance:		Recessive

Phenotypes

View phenotypes and curated references for all genotypes (concatenated display).

Expression

In Mice Carrying this Mutation:	10 assay results
In Structures Affected by this Mutation:	22 anatomical structure(s)

Tumor Data

List all tumor models in MMHCdb carrying Kcnj6^wv

Find Mice (IMSR)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 2 strains available Cell Lines: 0 lines available
Carrying any Kcnj6 Mutation:	26 strains or lines available

References

Original:	J:13422 Lane PW, Weaver, wv. Mouse News Lett. 1964;30:32
All:	208 reference(s)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 11/19/2024 MGI 6.24