Rab38<cht> Spontaneous Allele Detail MGI Mouse (MGI:1856819)

Rab38^cht
Spontaneous Allele Detail

Summary

Symbol:	Rab38^cht
Name:	RAB38, member RAS oncogene family; chocolate
MGI ID:	MGI:1856819
Synonyms:	chocolate, cht
Gene:	Rab38 Location: Chr7:88079481-88140780 bp, + strand Genetic Position: Chr7, 49.19 cM
Alliance:	Rab38^cht page

Brown coat color in Rab38^cht/Rab38^cht mice (right)

Show the 3 phenotype image(s) involving this allele.

Mutation
origin

Strain of Origin:

C57BL/6J

Mutation
description

Allele Type:		Spontaneous
Mutation:		Single point mutation
		Mutation details: A G-to-T transversion mutation at coding nucleotide 56 (c.56G>T) in exon 1 results in a glycine to valine substitution in codon 19 of the gene (p.G19V). This mutation lies within the highly conserved phosphate/Mg²⁺ domain. (J:75774)
Inheritance:		Recessive

Phenotypes

View phenotypes and curated references for all genotypes (concatenated display).

Expression

In Structures Affected by this Mutation:

Find Mice (IMSR)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available Cell Lines: 0 lines available
Carrying any Rab38 Mutation:	15 strains or lines available

Notes

This allele has been maintained on the C57BL/6J background at The Jackson Laboratory since 1984 when it was first identified.

References

Original:	J:13967 MacPike A, et al., New coat color mutations, Dbr and cht. Mouse News Lett. 1984;70:86
All:	12 reference(s)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 11/12/2024 MGI 6.24