Summary | Mutation origin | Mutation description | Expression | Phenotypes | Disease models | Tumor data | Find Mice (IMSR) | Notes | References

Symbol:	Prop1df
Name:	paired like homeodomain factor 1; Ames dwarf
MGI ID:	MGI:1856842
Synonyms:	Amesdf, df, DW, Prop1-
Gene:	Prop1  Location: Chr11:50841633-50844584 bp, - strand  Genetic Position: Chr11, 30.95 cM
Alliance:	Prop1df page

Strain of Origin:

Goodale large mice x pink-eyed stock

Allele Type:    Spontaneous Mutation:    Single point mutation   Mutation details: A T-to-C mutation results in a serine to proline substitution at position 83 (p.S83P) within the alpha1 helix in the homeodomain of the encoded peptide. (J:36967) Inheritance:    Recessive

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:	141 assay results 7 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	12 anatomical structure(s)

List all tumor models in MMHCdb carrying Prop1df

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 2 strains available      Cell Lines: 0 lines available
Carrying any Prop1 Mutation:	15 strains or lines available

Original:	J:64260 Schaible RH, et al., df - Ames dwarf. Mouse News Lett. 1961;25:35
All:	128 reference(s)