Qki<qk-k2> Chemically induced Allele Detail MGI Mouse (MGI:1857100)

Qki^qk-k2
Chemically induced Allele Detail

Summary

Symbol:	Qki^qk-k2
Name:	quaking, KH domain containing RNA binding; quaking k2
MGI ID:	MGI:1857100
Synonyms:	qk^k2
Gene:	Qki Location: Chr17:10425480-10538706 bp, - strand Genetic Position: Chr17, 7.75 cM
Alliance:	Qki^qk-k2 page

Growth retardation and impaired vascular development in Qki^qk-l1/Qki^qk-l1 and Qki^qk-k2/Qki^qk-k2 embryos

Show the 1 phenotype image(s) involving this allele.

Mutation
origin

Strain of Origin:

Mutation
description

Allele Type:		Chemically induced (ENU)
Mutation:		Single point mutation
		Mutation details: The mutation underlying the phenotype of Qk^k2 has been attributed to a T to A transversion at nucleotide 977, resulting in a missense mutation. The mutation was induced in a (C57BL/6 x CBA/Ca)F1 mouse and sequence analysis revealed the mutation orginated in the C57BL/6J allele. (J:55007)
Inheritance:		Recessive

Phenotypes

View phenotypes and curated references for all genotypes (concatenated display).

Find Mice (IMSR)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available Cell Lines: 0 lines available
Carrying any Qki Mutation:	28 strains or lines available

References

Original:	J:27474 Justice MJ, et al., Three ENU-induced alleles of the murine quaking locus are recessive embryonic lethal mutations. Genet Res. 1988 Apr;51(2):95-102
All:	6 reference(s)

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