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Hprt1b-m1
Transgenic Allele Detail
Summary
Symbol: Hprt1b-m1
Name: hypoxanthine phosphoribosyltransferase 1; hypoxanthine guanine phosphoribosyl transferase B, mutation 1
MGI ID: MGI:1857297
Synonyms: Hprt-bm1
Gene: Hprt1  Location: ChrX:52077014-52110536 bp, + strand  Genetic Position: ChrX, 29.31 cM, cytoband A6
Alliance: Hprt1b-m1 page
Transgene
origin
Germline Transmission:  Earliest citation of germline transmission: J:15485
Parent Cell Line:  CCE/EK.CCE (ES Cell)
Strain of Origin:  129S/SvEv-Gpi1c
Transgene
description
Transgene Type:    Transgenic (Null/knockout)
Mutation:    Insertion
    A retroviral sequence was inserted into intron 1 in ES cells carrying Hprtb. (J:3354)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Hprt1 Mutation:  1279 strains or lines available
References
Original:  J:15485 Kuehn MR, et al., A potential animal model for Lesch-Nyhan syndrome through introduction of HPRT mutations into mice. Nature. 1987 Mar 19-25;326(6110):295-8
All:  7 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory