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Hoxb4tm1Bay
Targeted Allele Detail
Summary
Symbol: Hoxb4tm1Bay
Name: homeobox B4; targeted mutation 1, Baylor College of Medicine
MGI ID: MGI:1857390
Synonyms: hoxb-4r
Gene: Hoxb4  Location: Chr11:96209093-96212464 bp, + strand  Genetic Position: Chr11, 59.83 cM
Alliance: Hoxb4tm1Bay page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:4612
Parent Cell Line:  AB2.1 (ES Cell)
Strain of Origin:  129S7/SvEvBrd-Hprt1b-m2
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Insertion
    Insertion of a gpt and neomycin cassette into exon 1. (J:4612)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 7 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Hoxb4 Mutation:  20 strains or lines available
References
Original:  J:4612 Ramirez-Solis R, et al., Hoxb-4 (Hox-2.6) mutant mice show homeotic transformation of a cervical vertebra and defects in the closure of the sternal rudiments. Cell. 1993 Apr 23;73(2):279-94
All:  5 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
12/10/2024
MGI 6.24
The Jackson Laboratory