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Ctnnb1tm1Max
Targeted Allele Detail
Summary
Symbol: Ctnnb1tm1Max
Name: catenin beta 1; targeted mutation 1, Max Planck Institut fur Immunbiologie
MGI ID: MGI:1857678
Synonyms: beta-cat -, beta-cateninn, Catnbtm1Kem
Gene: Ctnnb1  Location: Chr9:120762466-120789573 bp, + strand  Genetic Position: Chr9, 72.19 cM
Alliance: Ctnnb1tm1Max page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:29881
Parent Cell Line:  R1 (ES Cell)
Strain of Origin:  (129X1/SvJ x 129S1/Sv)F1-Kitl+
Mutation
description
Allele Type:    Targeted (Null/knockout, Reporter)
Mutations:    Insertion, Intragenic deletion
 
Mutation details: An IRES-Betageo cassette replaced exon 2 and part of exon 3. Immunofluorescence studies using affinity purified anti-peptide antibodies detected only residual maternal Beta-catenin in homozygous mutant 5.5-day postcoitum expanded blastocysts. (J:29881)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 4 assay results
In Structures Affected by this Mutation: 12 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Ctnnb1 Mutation:  49 strains or lines available
References
Original:  J:29881 Haegel H, et al., Lack of beta-catenin affects mouse development at gastrulation. Development. 1995 Nov;121(11):3529-37
All:  11 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory