Etn2<Sd> Spontaneous Allele Detail MGI Mouse (MGI:1857746)

Etn2^Sd
Spontaneous Allele Detail

Summary

Symbol:	Etn2^Sd
Name:	early transposon element insertion site 2; short Danforth
MGI ID:	MGI:1857746
Synonyms:	Sd(short-Danforth)
Gene:	Etn2 Location: unknown Genetic Position: Chr2, Syntenic
Alliance:	Etn2^Sd page

Etn2^Sd/+

Show the 1 phenotype image(s) involving this allele.

Mutation
origin

Strain of Origin:

Danforth's posterior duplication stock

Mutation
description

Allele Type:		Spontaneous
Mutation:		Transposon insertion
		Mutation details: A retrotransposon highly homologous to murine early transposon (ETn) endogenous retrovirus (ERV) 3 (ETnERV3) inserted 12 kb upstream of Ptf1a resulting in over-expression. The transposon insertion also results in the over-expression of Gm13344 and Gm13336. (J:195133, J:195196, J:195197)
Inheritance:		Semidominant

Phenotypes

View phenotypes and curated references for all genotypes (concatenated display).

Expression

In Mice Carrying this Mutation:	347 assay results 1 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	20 anatomical structure(s)

Find Mice (IMSR)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 3 strains available Cell Lines: 0 lines available
Carrying any Etn2 Mutation:	3 strains or lines available

Notes

Phenotypic Similarity to Human Syndrome: Caudal regression syndrome (J:195133)

References

Original:	J:13055 Dunn LC, et al., A new mutation in the mouse affecting spinal column and urogenital system. J Hered. 1940;31(8):343-348
All:	33 reference(s)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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