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Apaf1Gt(IRESBetageo)XIX18Pgr
Gene trapped Allele Detail
Summary
Symbol: Apaf1Gt(IRESBetageo)XIX18Pgr
Name: apoptotic peptidase activating factor 1; gene trap XIX18, Peter Gruss
MGI ID: MGI:1857868
Synonyms: Apaf1-, Apaf1tm1Pgr
Gene: Apaf1  Location: Chr10:90825173-90918632 bp, - strand  Genetic Position: Chr10, 45.47 cM, cytoband C3-D1
Alliance: Apaf1Gt(IRESBetageo)XIX18Pgr page
Mutation
origin
Mutant Cell Line:  XIX18
Germline Transmission:  Earliest citation of germline transmission: J:49840
Parent Cell Line:  R1 (ES Cell)
Strain of Origin:  (129X1/SvJ x 129S1/Sv)F1-Kitl+
Mutation
description
Allele Type:    Gene trapped (Null/knockout, Reporter)
Mutation:    Insertion of gene trap vector     Vector: pSABetageo     Vector Type: gene trap
 
Mutation details: Insertion of a gene trap vector at the 3' end of the gene downstream of the position corresponding to amino acid 1018. (J:49840)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Disease models
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Expression
In Mice Carrying this Mutation: 17 assay results
In Structures Affected by this Mutation: 15 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Apaf1 Mutation:  78 strains or lines available
References
Original:  J:40076 Chowdhury K, et al., Evidence for the stochastic integration of gene trap vectors into the mouse germline. Nucleic Acids Res. 1997 Apr 15;25(8):1531-6
All:  19 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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11/12/2024
MGI 6.24 		The Jackson Laboratory