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Foxc1tm1Blh
Targeted Allele Detail
Summary
Symbol: Foxc1tm1Blh
Name: forkhead box C1; targeted mutation 1, Brigid L Hogan
MGI ID: MGI:1857869
Synonyms: Foxc1-, Foxc1Lacz, Mf1-, Mf1lacZ
Gene: Foxc1  Location: Chr13:31990629-31994618 bp, + strand  Genetic Position: Chr13, 13.52 cM
Alliance: Foxc1tm1Blh page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:48079
Parent Cell Line:  TL1/TL-1 (ES Cell)
Strain of Origin:  129S6/SvEvTac
Mutation
description
Allele Type:    Targeted (Null/knockout, Reporter)
Mutations:    Insertion, Intragenic deletion
 
Mutation details: A lacZ- neomycin resistance cassette replaced sequences encoding amino acids 90-553 and most of the 3' untranslated region. A beta galactosidase fusion protein is expressed from this allele. (J:48079)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Disease models
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Expression
In Mice Carrying this Mutation: 309 assay results
1 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation: 49 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Foxc1 Mutation:  29 strains or lines available
References
Original:  J:48079 Kume T, et al., The forkhead/winged helix gene Mf1 is disrupted in the pleiotropic mouse mutation congenital hydrocephalus. Cell. 1998 Jun 12;93(6):985-96
All:  33 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory