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Pik3cgtm1Wym
Targeted Allele Detail
Summary
Symbol: Pik3cgtm1Wym
Name: phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma; targeted mutation 1, Matthias P Wymann
MGI ID: MGI:1858012
Synonyms: p110gamma-, PI3Kgamma-, PI3KgammaKO
Gene: Pik3cg  Location: Chr12:32223472-32258658 bp, - strand  Genetic Position: Chr12, 13.74 cM, cytoband B
Alliance: Pik3cgtm1Wym page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:60349
Parent Cell Line:  R1 (ES Cell)
Strain of Origin:  (129X1/SvJ x 129S1/Sv)F1-Kitl+
Mutation
description
Allele Type:    Targeted (Null/knockout, Reporter)
Mutation:    Insertion
    An IRES-LacZ-neo cassette was inserted into exon 2 via homologous recombination. (J:60349)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 1 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Pik3cg Mutation:  59 strains or lines available
References
Original:  J:60349 Hirsch E, et al., Central role for G protein-coupled phosphoinositide 3-kinase gamma in inflammation [see comments]. Science. 2000 Feb 11;287(5455):1049-53
All:  79 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/17/2024
MGI 6.24 		The Jackson Laboratory