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Lhx9tm1Lmgd
Targeted Allele Detail
Summary
Symbol: Lhx9tm1Lmgd
Name: LIM homeobox protein 9; targeted mutation 1, Laboratory of Mammalian Genes and Development, Heiner Westphal
MGI ID: MGI:1888554
Synonyms: Lhx9-
Gene: Lhx9  Location: Chr1:138752924-138776315 bp, - strand  Genetic Position: Chr1, 60.82 cM, cytoband G-H2
Alliance: Lhx9tm1Lmgd page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:60621
Parent Cell Line:  R1 (ES Cell)
Strain of Origin:  (129X1/SvJ x 129S1/Sv)F1-Kitl+
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation details: A neomycin resistance cassette replaced exons 2 and 3 of the gene, which encode the first and second LIM domains of the protein. (J:60621)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 5 assay results
In Structures Affected by this Mutation: 9 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 2 strains available      Cell Lines: 0 lines available
Carrying any Lhx9 Mutation:  31 strains or lines available
References
Original:  J:60621 Birk OS, et al., The LIM homeobox gene Lhx9 is essential for mouse gonad formation. Nature. 2000 Feb 24;403(6772):909-13
All:  3 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory