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Gcm2tm1Kry
Targeted Allele Detail
Summary
Symbol: Gcm2tm1Kry
Name: glial cells missing homolog 2; targeted mutation 1, Gerard Karsenty
MGI ID: MGI:1889069
Synonyms: Gcm2m1
Gene: Gcm2  Location: Chr13:41254903-41264511 bp, - strand  Genetic Position: Chr13, 20.31 cM
Alliance: Gcm2tm1Kry page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:63291
Parent Cell Line:  AB1 (ES Cell)
Strain of Origin:  129S7/SvEvBrd-Hprt1+
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsA neomycin resistance cassette replaced all four exons of the gene. RT-PCR did not amplify a product from the neck region of homozygous mutant mice. (J:63291)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Disease models
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Expression
In Mice Carrying this Mutation: 58 assay results
In Structures Affected by this Mutation: 7 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Gcm2 Mutation:  34 strains or lines available
References
Original:  J:63291 Gunther T, et al., Genetic ablation of parathyroid glands reveals another source of parathyroid hormone. Nature. 2000 Jul 13;406(6792):199-203
All:  11 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
07/05/2024
MGI 6.24
The Jackson Laboratory