Ppardtm1Jps
Targeted Allele Detail
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| Symbol: |
Ppardtm1Jps |
| Name: |
peroxisome proliferator activator receptor delta; targeted mutation 1, Jeffrey M Peters |
| MGI ID: |
MGI:1889516 |
| Synonyms: |
PPARbeta-, Pparbeta/delta-null |
| Gene: |
Ppard Location: Chr17:28451715-28520446 bp, + strand Genetic Position: Chr17, 14.64 cM
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| Alliance: |
Ppardtm1Jps page
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| Germline Transmission: |
Earliest citation of germline transmission:
J:63040
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| Parent Cell Line: |
Not Specified (ES Cell)
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| Strain of Origin: |
129/Sv
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| Allele Type: |
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Targeted (Null/knockout) |
| Mutation: |
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Insertion
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Mutation details: The last exon of this gene was disrupted by insertion of a neomycin resistance cassette via homologous recombination. Mutant transcript was detected in adipose, brain, and skin tissue from homozygous mutant animals by Northern blot analysis, but protein product was not detect in hepatic nuclear extract by Western blot analysis.
(J:63040)
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View phenotypes and curated references for all genotypes (concatenated display).
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Carrying any Ppard Mutation: |
68 strains or lines available
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| Original: |
J:63040 Peters JM, et al., Growth, adipose, brain, and skin alterations resulting from targeted disruption of the mouse peroxisome proliferator-activated receptor beta(delta). Mol Cell Biol. 2000 Jul;20(14):5119-28 |
| All: |
37 reference(s) |
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Analysis Tools
