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Fetub Gene Detail
Summary
  • Symbol
    Fetub
  • Name
    fetuin beta
  • Synonyms
    2310011O17Rik, D17980
  • Feature Type
    protein coding gene
  • IDs
    MGI:1890221
    NCBI Gene: 59083
  • Alliance
    gene page
  • Transcription Start Sites
    20 TSS
Location &
Maps
more
  • Sequence Map
    Chr16:22737132-22758518 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 16, 13.76 cM, cytoband B
  • Mapping Data
    4 experiments
Strain
Comparison
more
  • SNPs within 2kb
    501 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1890221
 protein coding gene Chr16:22737084-22758528 (+)
129S1/SvImJ MGP_129S1SvImJ_G0022675
 protein coding gene Chr16:20448610-20466660 (+)
A/J MGP_AJ_G0022636
 protein coding gene Chr16:19458103-19477999 (+)
AKR/J MGP_AKRJ_G0022611
 protein coding gene Chr16:20248620-20291766 (+)
BALB/cJ MGP_BALBcJ_G0022641
 protein coding gene Chr16:19659267-19676556 (+)
C3H/HeJ MGP_C3HHeJ_G0022405
 protein coding gene Chr16:20354075-20399082 (+)
C57BL/6NJ MGP_C57BL6NJ_G0023091
 protein coding gene Chr16:20900549-20910976 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0020609
 protein coding gene Chr16:20151780-20166720 (+)
CAST/EiJ MGP_CASTEiJ_G0021935
 protein coding gene Chr16:20379615-20396403 (+)
CBA/J MGP_CBAJ_G0022377
 protein coding gene Chr16:21733561-21784390 (+)
DBA/2J MGP_DBA2J_G0022509
 protein coding gene Chr16:19439159-19454363 (+)
FVB/NJ MGP_FVBNJ_G0022485
 protein coding gene Chr16:19408668-19430199 (+)
LP/J MGP_LPJ_G0022577
 protein coding gene Chr16:20198492-20217351 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0022504
 protein coding gene Chr16:21304712-21320722 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0023102
 protein coding gene Chr16:20218760-20235189 (+)
PWK/PhJ MGP_PWKPhJ_G0021675
 protein coding gene Chr16:19683242-19698444 (+)
SPRET/EiJ MGP_SPRETEiJ_G0021505
 protein coding gene Chr16:20008945-20023669 (+)
WSB/EiJ MGP_WSBEiJ_G0021978
 protein coding gene Chr16:20187475-20202362 (+)



Homology
more
  • Human Ortholog
    FETUB, fetuin B
  • Vertebrate Orthologs
    5
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    FETUB, fetuin B
  • Synonyms
    16G2, Gugu, IRL685
  • Links
    NCBI Gene ID: 26998
    neXtProt AC: NX_Q9UGM5
    UniProt: Q9UGM5

  • Chr Location
    3q27.3; chr3:186635969-186653141 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotypes from 1 allele in 2 genetic backgrounds
    6 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a knock-out allele exhibit female infertility due to premature hardening of the zona pellucida.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    10
  • GO References
    3
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    764
  • Tissues
    17
  • cDNA Data
    81
  • Literature Summary
    3
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 59083 NCBI Gene Model | MGI Sequence Detail 21387 C57BL/6J ±  kb
    transcript NM_021564 RefSeq | MGI Sequence Detail 1600 ZRU/MplStud  
    polypeptide Q9QXC1 UniProt | EBI | MGI Sequence Detail 388 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 84
      cDNA 83
      Primer pair 1

      Microarray probesets 3
    Other
    Accession IDs
    less
    MGI:1915165, MGI:2146393
    References
    more
    • Summaries
      All 33
      Developmental Gene Expression 3
      Gene Ontology 3
      Phenotypes 6
    • Earliest
      J:64478 Olivier E, et al., Fetuin-B, a second member of the fetuin family in mammals. Biochem J. 2000 Sep 1;350 Pt 2:589-97
    • Latest
      J:326541 Cyagen Biosciences Inc., Cyagen Biosciences Website. 2022;
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    12/17/2024
    MGI 6.24     		The Jackson Laboratory