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Midn Gene Detail
Summary
  • Symbol
    Midn
  • Name
    midnolin
  • Synonyms
    3000003C15Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1890222
    NCBI Gene: 59090
  • Alliance
    gene page
  • Transcription Start Sites
    17 TSS
Location &
Maps
more
  • Sequence Map
    Chr10:79984106-79994202 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 10, 39.72 cM, cytoband C1
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    163 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1890222
 protein coding gene Chr10:79984106-79994202 (+)
129S1/SvImJ MGP_129S1SvImJ_G0017485
 protein coding gene Chr10:80733413-80743845 (+)
A/J MGP_AJ_G0017463
 protein coding gene Chr10:77909922-77920108 (+)
AKR/J MGP_AKRJ_G0017424
 protein coding gene Chr10:80038216-80048449 (+)
BALB/cJ MGP_BALBcJ_G0017425
 protein coding gene Chr10:78133571-78143677 (+)
C3H/HeJ MGP_C3HHeJ_G0017248
 protein coding gene Chr10:80136868-80146959 (+)
C57BL/6NJ MGP_C57BL6NJ_G0017879
 protein coding gene Chr10:83516117-83526219 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0015567
 protein coding gene Chr10:74135007-74145144 (+)
CAST/EiJ MGP_CASTEiJ_G0016815
 protein coding gene Chr10:80339854-80352269 (+)
CBA/J MGP_CBAJ_G0017220
 protein coding gene Chr10:86755387-86765513 (+)
DBA/2J MGP_DBA2J_G0017326
 protein coding gene Chr10:77127917-77139923 (+)
FVB/NJ MGP_FVBNJ_G0017320
 protein coding gene Chr10:76312183-76322604 (+)
LP/J MGP_LPJ_G0017397
 protein coding gene Chr10:81212781-81223768 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0017346
 protein coding gene Chr10:88706037-88715967 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0017920
 protein coding gene Chr10:80018721-80028826 (+)
PWK/PhJ MGP_PWKPhJ_G0016596
 protein coding gene Chr10:76994968-77005334 (+)
SPRET/EiJ MGP_SPRETEiJ_G0016385
 protein coding gene Chr10:78999677-79009771 (+)
WSB/EiJ MGP_WSBEiJ_G0016875
 protein coding gene Chr10:80052535-80064268 (+)



Homology
more
  • Human Ortholog
    MIDN, midnolin
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotypes from 2 alleles in 2 genetic backgrounds
    16 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a transgenic gene disruption exhibit cleft palate and small ovary.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    12
  • GO References
    4
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    732
  • Tissues
    25
  • cDNA Data
    55
  • Literature Summary
    3
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 59090 NCBI Gene Model | MGI Sequence Detail 10097 C57BL/6J ±  kb
    transcript NM_021565 RefSeq | MGI Sequence Detail 3747 Not Specified  
    polypeptide Q3TPJ7 UniProt | EBI | MGI Sequence Detail 465 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 56
      cDNA 55
      Primer pair 1

      Microarray probesets 3
    Other
    Accession IDs
    less
    MGI:1917443
    References
    more
    • Summaries
      All 41
      Developmental Gene Expression 3
      Gene Ontology 4
      Phenotypes 16
    • Earliest
      J:137335 Roderick TH, Chromosomal inversions in studies of mammalian mutagenesis. Genetics. 1979 May;92(1 Pt 1 Suppl):s121-6
    • Latest
      J:349474 Zhong X, et al., Viable mutations of mouse midnolin suppress B cell malignancies. J Exp Med. 2024 Jun 3;221(6)
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    11/12/2024
    MGI 6.24     		The Jackson Laboratory