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Dynlt2b Gene Detail
Summary
  • Symbol
    Dynlt2b
  • Name
    dynein light chain Tctex-type 2B
  • Synonyms
    0610012D17Rik, 2410011K15Rik, Tctex1d2
  • Feature Type
    protein coding gene
  • IDs
    MGI:1913311
    NCBI Gene: 66061
  • Alliance
    gene page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr16:32238520-32247917 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 16, 22.69 cM, cytoband B2
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    295 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1913311
 protein coding gene Chr16:32238520-32247917 (+)
129S1/SvImJ MGP_129S1SvImJ_G0022738
 protein coding gene Chr16:30497442-30506767 (+)
A/J MGP_AJ_G0022703
 protein coding gene Chr16:29050730-29060007 (+)
AKR/J MGP_AKRJ_G0022676
 protein coding gene Chr16:30110592-30120753 (+)
BALB/cJ MGP_BALBcJ_G0022705
 protein coding gene Chr16:29199766-29209046 (+)
C3H/HeJ MGP_C3HHeJ_G0022470
 protein coding gene Chr16:30237886-30247626 (+)
C57BL/6NJ MGP_C57BL6NJ_G0023154
 protein coding gene Chr16:31146987-31156279 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0020672
 protein coding gene Chr16:29429216-29438231 (+)
CAST/EiJ MGP_CASTEiJ_G0021998
 protein coding gene Chr16:30364188-30375035 (+)
CBA/J MGP_CBAJ_G0022440
 protein coding gene Chr16:32393525-32402833 (+)
DBA/2J MGP_DBA2J_G0022573
 protein coding gene Chr16:28899016-28908375 (+)
FVB/NJ MGP_FVBNJ_G0022548
 protein coding gene Chr16:28889404-28898707 (+)
LP/J MGP_LPJ_G0022640
 protein coding gene Chr16:30257999-30267857 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0022567
 protein coding gene Chr16:31838088-31847361 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0023166
 protein coding gene Chr16:30097106-30106382 (+)
PWK/PhJ MGP_PWKPhJ_G0021737
 protein coding gene Chr16:29220035-29229555 (+)
SPRET/EiJ MGP_SPRETEiJ_G0021568
 protein coding gene Chr16:29881990-29891085 (+)
WSB/EiJ MGP_WSBEiJ_G0022042
 protein coding gene Chr16:30039861-30052239 (+)



Homology
more
  • Human Ortholog
    DYNLT2B, dynein light chain Tctex-type 2B
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    DYNLT2B, dynein light chain Tctex-type 2B
  • Synonyms
    SRTD17, TCTEX1D2
  • Links
    NCBI Gene ID: 255758
    neXtProt AC: NX_Q8WW35
    UniProt: Q8WW35

  • Chr Location
    3q29; chr3:196291219-196318299 (-)  GRCh38
Human Diseases
more
  • Diseases
    1 with human DYNLT2B associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotypes from 2 alleles in 2 genetic backgrounds
    13 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    18
  • GO References
    5
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    714
  • Tissues
    4
  • cDNA Data
    30
  • Literature Summary
    2
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 66061 NCBI Gene Model | MGI Sequence Detail 9398 C57BL/6J ±  kb
    transcript NM_025329 RefSeq | MGI Sequence Detail 854 Not Specified  
    polypeptide Q9CQ66 UniProt | EBI | MGI Sequence Detail 144 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 30
      cDNA 30

      Microarray probesets 4
    Other
    Accession IDs
    less
    MGI:1913668, MGI:6458571
    References
    more
    • Summaries
      All 39
      Developmental Gene Expression 2
      Gene Ontology 5
      Phenotypes 13
    • Earliest
      J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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    Funding Information
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    Send questions and comments to User Support.     		last database update
    12/10/2024
    MGI 6.24     		The Jackson Laboratory