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Ube2l6 Gene Detail
Summary
  • Symbol
    Ube2l6
  • Name
    ubiquitin-conjugating enzyme E2L 6
  • Synonyms
    2810489I21Rik, RIG-B, Ubce8, UBCH8, Ubcm8
  • Feature Type
    protein coding gene
  • IDs
    MGI:1914500
    NCBI Gene: 56791
  • Alliance
    gene page
  • Transcription Start Sites
    12 TSS
Location &
Maps
more
  • Sequence Map
    Chr2:84629172-84640347 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 2, 49.45 cM, cytoband E1
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    349 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1914500
 protein coding gene Chr2:84629172-84640679 (+)
129S1/SvImJ MGP_129S1SvImJ_G0025911
 protein coding gene Chr2:85493979-85508074 (+)
A/J MGP_AJ_G0025885
 protein coding gene Chr2:82192577-82204077 (+)
AKR/J MGP_AKRJ_G0025855
 protein coding gene Chr2:84307169-84322766 (+)
BALB/cJ MGP_BALBcJ_G0025882
 protein coding gene Chr2:82317604-82330637 (+)
C3H/HeJ MGP_C3HHeJ_G0025641
 protein coding gene Chr2:84548099-84562066 (+)
C57BL/6NJ MGP_C57BL6NJ_G0026328
 protein coding gene Chr2:88141535-88157763 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0023730
 protein coding gene Chr2:79009805-79020362 (+)
CAST/EiJ MGP_CASTEiJ_G0025102
 protein coding gene Chr2:85080427-85095331 (+)
CBA/J MGP_CBAJ_G0025622
 protein coding gene Chr2:91296337-91308077 (+)
DBA/2J MGP_DBA2J_G0025753
 protein coding gene Chr2:81723562-81735380 (+)
FVB/NJ MGP_FVBNJ_G0025716
 protein coding gene Chr2:80979347-80990607 (+)
LP/J MGP_LPJ_G0025841
 protein coding gene Chr2:85290331-85304708 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0025746
 protein coding gene Chr2:93610316-93626045 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0026384
 protein coding gene Chr2:84548746-84563565 (+)
PWK/PhJ MGP_PWKPhJ_G0024846
 protein coding gene Chr2:81566823-81579258 (+)
SPRET/EiJ MGP_SPRETEiJ_G0024650
 protein coding gene Chr2:84686827-84700867 (+)
WSB/EiJ MGP_WSBEiJ_G0025172
 protein coding gene Chr2:85210030-85223054 (+)



Homology
more
  • Human Ortholog
    UBE2L6, ubiquitin conjugating enzyme E2 L6
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    UBE2L6, ubiquitin conjugating enzyme E2 L6
  • Synonyms
    RIG-B, UBCH8
  • Links
    NCBI Gene ID: 9246
    neXtProt AC: NX_O14933
    UniProt: O14933

  • Chr Location
    11q12.1; chr11:57551656-57568284 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    12 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    19
  • GO References
    8
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    729
  • Tissues
    1
  • cDNA Data
    85
  • Literature Summary
    1
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 56791 NCBI Gene Model | MGI Sequence Detail 11176 C57BL/6J ±  kb
transcript NM_019949 RefSeq | MGI Sequence Detail 1402 C57BL/6  
polypeptide Q9QZU9 UniProt | EBI | MGI Sequence Detail 153 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 85
    cDNA 85

    Microarray probesets 5
References
more
  • Summaries
    All 47
    Developmental Gene Expression 1
    Gene Ontology 8
    Phenotypes 12
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:269738 Guerreiro I, et al., Reorganisation of Hoxd regulatory landscapes during the evolution of a snake-like body plan. Elife. 2016 Aug 1;5:e16087
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/05/2024
MGI 6.24 		The Jackson Laboratory