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Isoc2b Gene Detail
Summary
  • Symbol
    Isoc2b
  • Name
    isochorismatase domain containing 2b
  • Synonyms
    0610042E07Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1914691
    NCBI Gene: 67441
  • Alliance
    gene page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr7:4847958-4869178 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 7, 2.80 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    708 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1914691
 protein coding gene Chr7:4847958-4873257 (-)
129S1/SvImJ MGP_129S1SvImJ_G0031566
 protein coding gene Chr7:1795295-1816582 (-)
A/J MGP_AJ_G0031540
 protein coding gene Chr7:1788965-1811972 (-)
AKR/J MGP_AKRJ_G0031469
 protein coding gene Chr7:1868523-1893336 (-)
BALB/cJ MGP_BALBcJ_G0031548
 protein coding gene Chr7:1830520-1852775 (-)
C3H/HeJ MGP_C3HHeJ_G0031269
 protein coding gene Chr7:1837911-1865233 (-)
C57BL/6NJ MGP_C57BL6NJ_G0032009
 protein coding gene Chr7:1853677-1878904 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0029133
 protein coding gene Chr7:1526315-1547407 (-)
CAST/EiJ MGP_CASTEiJ_G0030633
 protein coding gene Chr7:1775632-1804110 (-)
CBA/J MGP_CBAJ_G0031227
 protein coding gene Chr7:2046066-2074846 (-)
DBA/2J MGP_DBA2J_G0031386
 protein coding gene Chr7:1762992-1789762 (-)
FVB/NJ MGP_FVBNJ_G0031338
 protein coding gene Chr7:1729311-1753520 (-)
LP/J MGP_LPJ_G0031471
 protein coding gene Chr7:1896169-1917568 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0031377
 protein coding gene Chr7:1994822-2027225 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0032039
 protein coding gene Chr7:1771851-1796469 (-)
PWK/PhJ MGP_PWKPhJ_G0030361
 protein coding gene Chr7:1935053-1957903 (-)
SPRET/EiJ MGP_SPRETEiJ_G0030186
 protein coding gene Chr7:1815518-1838397 (-)
WSB/EiJ MGP_WSBEiJ_G0030728
 protein coding gene Chr7:1786970-1809154 (-)



Homology
more
  • Human Ortholog
    ISOC2, isochorismatase domain containing 2
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    ISOC2, isochorismatase domain containing 2
  • Links
    NCBI Gene ID: 79763
    neXtProt AC: NX_Q96AB3
    UniProt: Q96AB3

  • Chr Location
    19q13.42; chr19:55452985-55462343 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    7 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    6
  • GO References
    5
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    14
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 67441 NCBI Gene Model | MGI Sequence Detail 21221 C57BL/6J ±  kb
transcript NM_026158 RefSeq | MGI Sequence Detail 1065 C57BL/6  
polypeptide Q9DCC7 UniProt | EBI | MGI Sequence Detail 210 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    1 Sequence
  • InterPro Domains
    IPR050993 Isochorismatase domain-containing protein
    IPR000868 Isochorismatase-like
    IPR036380 Isochorismatase-like superfamily
Molecular
Reagents
less
  • All nucleic 14
    cDNA 14

    Microarray probesets 3
Other
Accession IDs
less
MGI:2141997
References
more
  • Summaries
    All 29
    Gene Ontology 5
    Phenotypes 7
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:326541 Cyagen Biosciences Inc., Cyagen Biosciences Website. 2022;
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
10/29/2024
MGI 6.24 		The Jackson Laboratory