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Polr3g Gene Detail
Summary
  • Symbol
    Polr3g
  • Name
    polymerase (RNA) III (DNA directed) polypeptide G
  • Synonyms
    2310047G20Rik, RPC32
  • Feature Type
    protein coding gene
  • IDs
    MGI:1914736
    NCBI Gene: 67486
  • Alliance
    gene page
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr13:81821962-81859132 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 13, 43.68 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    1307 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1914736
 protein coding gene Chr13:81821956-81859132 (-)
129S1/SvImJ MGP_129S1SvImJ_G0020788
 protein coding gene Chr13:82441108-82480180 (-)
A/J MGP_AJ_G0020744
 protein coding gene Chr13:79568984-79606693 (-)
AKR/J MGP_AKRJ_G0020717
 protein coding gene Chr13:81923008-81960082 (-)
BALB/cJ MGP_BALBcJ_G0020740
 protein coding gene Chr13:80112384-80149430 (-)
C3H/HeJ MGP_C3HHeJ_G0020534
 protein coding gene Chr13:81669597-81707241 (-)
C57BL/6NJ MGP_C57BL6NJ_G0021177
 protein coding gene Chr13:85122277-85159239 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0018745
 protein coding gene Chr13:76035461-76075200 (-)
CAST/EiJ MGP_CASTEiJ_G0020052
 protein coding gene Chr13:80763427-80800208 (-)
CBA/J MGP_CBAJ_G0020493
 protein coding gene Chr13:88351439-88395746 (-)
DBA/2J MGP_DBA2J_G0020618
 protein coding gene Chr13:79221538-79258967 (-)
FVB/NJ MGP_FVBNJ_G0020598
 protein coding gene Chr13:78307223-78344265 (-)
LP/J MGP_LPJ_G0020691
 protein coding gene Chr13:82663272-82701090 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0020627
 protein coding gene Chr13:87261340-87299724 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0021217
 protein coding gene Chr13:81340643-81382030 (-)
PWK/PhJ MGP_PWKPhJ_G0019805
 protein coding gene Chr13:78139140-78174741 (-)
SPRET/EiJ MGP_SPRETEiJ_G0019628
 protein coding gene Chr13:77582724-77620642 (-)
WSB/EiJ MGP_WSBEiJ_G0020109
 protein coding gene Chr13:81771994-81810763 (-)



Homology
more
  • Human Ortholog
    POLR3G, RNA polymerase III subunit G
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    POLR3G, RNA polymerase III subunit G
  • Synonyms
    C31, RPC32, RPC7
  • Links
    NCBI Gene ID: 10622
    neXtProt AC: NX_O15318
    UniProt: O15318

  • Chr Location
    5q14.3; chr5:90471748-90514557 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotypes from 2 alleles in 2 genetic backgrounds
    2 phenotypes from multigenic genotypes
    17 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a null allele exhibit embryonic lethality between E3.5 and E6.5.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    21
  • GO References
    7
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    801
  • Tissues
    95
  • cDNA Data
    66
  • Literature Summary
    2
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000035834 Ensembl Gene Model | MGI Sequence Detail 37171 C57BL/6J ±  kb
transcript ENSMUST00000048993 Ensembl | MGI Sequence Detail 3054 Not Applicable  
polypeptide ENSMUSP00000035289 Ensembl | MGI Sequence Detail 223 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 68
    cDNA 66
    Primer pair 1
    Other 1

    Microarray probesets 1
Other
Accession IDs
less
MGI:2145397
References
more
  • Summaries
    All 46
    Developmental Gene Expression 2
    Gene Ontology 7
    Phenotypes 17
  • Earliest
    J:182573 Roderick TH, Producing and detecting paracentric chromosomal inversions in mice. Mutat Res. 1971 Jan;11(1):59-69
  • Latest
    J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
10/29/2024
MGI 6.24 		The Jackson Laboratory